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10.1016/j.celrep.2016.05.009 http://scihub22266oqcxt.onion/10.1016/j.celrep.2016.05.009 C4899145!4899145!27239035     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27239035&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Rep 2016 ; 15 (10): 2136-46 Nephropedia Template TP {{tp|p=27239035|t=2016. Diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms |pdf=|usr=}}{{27239035}} gab.com Text Diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms JO: Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=27239035 #FOAvip Dietary interventions have not been effective in the treatment of multiple sclerosis (MS). Here we show that periodic 3 day cycles of a fasting mimicking diet (FMD) are effective in ameliorating demyelination and symptoms in a murine experimental autoimmune encephalomyelitis (EAE) model. The FMD reduced clinical severity in all mice, and completely reversed symptoms in 20% of the animals. These improvements were associated with increased corticosterone levels and Treg cell number, reduced levels of pro-inflammatory cytokines, TH1 and TH17 cells, and antigen presenting cells (APCs). Moreover, the FMD promoted oligodendrocyte precursor cell regeneration and remyelination in axons in response to both EAE and cuprizone MS models, supporting its effects on both suppression of autoimmunity and remyelination. We also report preliminary data suggesting that a FMD or a chronic ketogenic diet are safe, feasible and potentially effective in the treatment of relapsing remitting multiple sclerosis (RRMS) patients (NCT01538355). Twit Text FOAVip Diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms ????Cell Rep http://www.kidney.de/pget.php?&tw=1&pmid=27239035 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27239035 #FOAvip English Wikipedia <ref>{{Cite pmid|27239035}}</ref> Diet mimicking fasting promotes regeneration and reduces autoimmunity and multiple sclerosis symptoms #MMPMID27239035 Choi IY; Piccio L; Childress P; Bollman B; Ghosh A; Brandhorst S; Suarez J; Michalsen A; Cross AH; Morgan TE; Wei M; Paul F; Bock M; Longo VD Cell Rep 2016[Jun]; 15 (10): 2136-46 PMID27239035show ga Dietary interventions have not been effective in the treatment of multiple sclerosis (MS). Here we show that periodic 3 day cycles of a fasting mimicking diet (FMD) are effective in ameliorating demyelination and symptoms in a murine experimental autoimmune encephalomyelitis (EAE) model. The FMD reduced clinical severity in all mice, and completely reversed symptoms in 20% of the animals. These improvements were associated with increased corticosterone levels and Treg cell number, reduced levels of pro-inflammatory cytokines, TH1 and TH17 cells, and antigen presenting cells (APCs). Moreover, the FMD promoted oligodendrocyte precursor cell regeneration and remyelination in axons in response to both EAE and cuprizone MS models, supporting its effects on both suppression of autoimmunity and remyelination. We also report preliminary data suggesting that a FMD or a chronic ketogenic diet are safe, feasible and potentially effective in the treatment of relapsing remitting multiple sclerosis (RRMS) patients (NCT01538355). äDiet mimicking fasting promotes regeneration and reduces autoimmunity (epmc).pdf DeepDyve Pubget Overpricing