Nat Cell Biol 2015[Dec]; 17 (12): 1517-9 PMID26612573show ga
A powerful combination of two-color imaging in vivo, fourier-filtered kymography, and simulations provides high-resolution view of kinesin-2 transport dynamics in cilia. This study reveals heterotrimeric kinesin-II as an obstacle course runner, homodimeric OSM-3/KIF17 as a long distance runner, and the baton handoff between these two motors on the microtubule track.