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10.1007/s00427-016-0542-7 http://scihub22266oqcxt.onion/10.1007/s00427-016-0542-7 C4896989!4896989 !27056385     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27056385 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Dev+Genes+Evol 2016 ; 226 (3 ): 209-19 Nephropedia Template TP {{tp|p=27056385 |t=2016. The insect central complex as model for heterochronic brain development-background, concepts, and tools |pdf=|usr=}}{{27056385 }} gab.com Text The insect central complex as model for heterochronic brain development-background, concepts, and tools JO: Dev Genes Evol http://www.kidney.de/pget.php?&tw=1&pmid=27056385 #FOAvip The adult insect brain is composed of neuropils present in most taxa. However, the relative size, shape, and developmental timing differ between species. This diversity of adult insect brain morphology has been extensively described while the genetic mechanisms of brain development are studied predominantly in Drosophila melanogaster. However, it has remained enigmatic what cellular and genetic mechanisms underlie the evolution of neuropil diversity or heterochronic development. In this perspective paper, we propose a novel approach to study these questions. We suggest using genome editing to mark homologous neural cells in the fly D. melanogaster, the beetle Tribolium castaneum, and the Mediterranean field cricket Gryllus bimaculatus to investigate developmental differences leading to brain diversification. One interesting aspect is the heterochrony observed in central complex development. Ancestrally, the central complex is formed during embryogenesis (as in Gryllus) but in Drosophila, it arises during late larval and metamorphic stages. In Tribolium, it forms partially during embryogenesis. Finally, we present tools for brain research in Tribolium including 3D reconstruction and immunohistochemistry data of first instar brains and the generation of transgenic brain imaging lines. Further, we characterize reporter lines labeling the mushroom bodies and reflecting the expression of the neuroblast marker gene Tc-asense, respectively. Twit Text FOAVip The insect central complex as model for heterochronic brain development-background, concepts, and tools ????Dev Genes Evol http://www.kidney.de/pget.php?&tw=1&pmid=27056385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27056385 #FOAvip English Wikipedia <ref>{{Cite pmid|27056385 }}</ref> The insect central complex as model for heterochronic brain development-background, concepts, and tools #MMPMID27056385 Koniszewski ND ; Kollmann M ; Bigham M ; Farnworth M ; He B ; Büscher M ; Hütteroth W ; Binzer M ; Schachtner J ; Bucher G Dev Genes Evol 2016[Jun]; 226 (3 ): 209-19 PMID27056385 show ga The adult insect brain is composed of neuropils present in most taxa. However, the relative size, shape, and developmental timing differ between species. This diversity of adult insect brain morphology has been extensively described while the genetic mechanisms of brain development are studied predominantly in Drosophila melanogaster. However, it has remained enigmatic what cellular and genetic mechanisms underlie the evolution of neuropil diversity or heterochronic development. In this perspective paper, we propose a novel approach to study these questions. We suggest using genome editing to mark homologous neural cells in the fly D. melanogaster, the beetle Tribolium castaneum, and the Mediterranean field cricket Gryllus bimaculatus to investigate developmental differences leading to brain diversification. One interesting aspect is the heterochrony observed in central complex development. Ancestrally, the central complex is formed during embryogenesis (as in Gryllus) but in Drosophila, it arises during late larval and metamorphic stages. In Tribolium, it forms partially during embryogenesis. Finally, we present tools for brain research in Tribolium including 3D reconstruction and immunohistochemistry data of first instar brains and the generation of transgenic brain imaging lines. Further, we characterize reporter lines labeling the mushroom bodies and reflecting the expression of the neuroblast marker gene Tc-asense, respectively. |Animals [MESH] |Animals, Genetically Modified [MESH] |Biological Evolution [MESH] |Brain/anatomy & histology/growth & development/physiology [MESH] |Gene Editing/*methods [MESH] |Insecta/*anatomy & histology/classification/growth & development/physiology [MESH] |Larva/anatomy & histology [MESH] |Mushroom Bodies/anatomy & histology/physiology [MESH] |Neuropil/*classification/cytology [MESH]The insect central complex as model for heterochronic brain developm(epmc).pdf DeepDyve Pubget Overpricing