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2016 ; 10
(ä): 52-68
Nephropedia Template TP
gab.com Text
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English Wikipedia
The Role of Neuroimaging Techniques in Establishing Diagnosis, Prognosis and
Therapy in Disorders of Consciousness
#MMPMID27347265
Gosseries O
; Pistoia F
; Charland-Verville V
; Carolei A
; Sacco S
; Laureys S
Open Neuroimag J
2016[]; 10
(ä): 52-68
PMID27347265
show ga
Non-communicative brain damaged patients raise important clinical and scientific
issues. Here, we review three major pathological disorders of consciousness:
coma, the unresponsive wakefulness syndrome and the minimally conscious state. A
number of clinical studies highlight the difficulty in making a correct diagnosis
in patients with disorders of consciousness based only on behavioral
examinations. The increasing use of neuroimaging techniques allows improving
clinical characterization of these patients. Recent neuroimaging studies using
positron emission tomography, functional magnetic resonance imaging,
electroencephalography and transcranial magnetic stimulation can help assess
diagnosis, prognosis, and therapeutic treatment. These techniques, using resting
state, passive and active paradigms, also highlight possible dissociations
between consciousness and responsiveness, and are facilitating a more accurate
understanding of brain function in this challenging population.