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10.1093/brain/aww056

http://scihub22266oqcxt.onion/10.1093/brain/aww056
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C4892750!4892750!27017187
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suck abstract from ncbi


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pmid27017187      Brain 2016 ; 139 (6): 1657-65
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  • Anti-ganglioside antibodies are removed from circulation in mice by neuronal endocytosis #MMPMID27017187
  • Cunningham ME; McGonigal R; Meehan GR; Barrie JA; Yao D; Halstead SK; Willison HJ
  • Brain 2016[Jun]; 139 (6): 1657-65 PMID27017187show ga
  • See van Doorn and Jacobs (doi:10.1093/brain/aww078) for a scientific commentary on this article. ?How does anti-ganglioside autoantibody clearance from the circulation affect their detection and neurotoxicity? Cunningham et al. describe an uptake pathway for these autoantibodies at motor nerve terminals and their delivery into the brain parenchyma. This highlights the limitations of serum antibody measurements and suggests a possible entry mechanism for their central effects.
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