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10.15412/J.BCN.03070207 http://scihub22266oqcxt.onion/10.15412/J.BCN.03070207 C4892318!4892318!27303608     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27303608&cmd=llinks): Failed to open stream: HTTP request failed! 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Elevated IL-17 and TGF-? Serum Levels: A Positive Correlation between T-helper 17 Cell-Related Pro-Inflammatory Responses with Major Depressive Disorder |pdf=|usr=}}{{27303608}} gab.com Text Elevated IL-17 and TGF- Serum Levels: A Positive Correlation between T-helper 17 Cell-Related Pro-Inflammatory Responses with Major Depressive Disorder JO: Basic Clin Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=27303608 #FOAvip Introduction:: Depression is a mental disorder that highly associated with immune system. Therefore, this study compares the serum concentrations of IL-21, IL-17, and transforming growth factor ? (TGF-?) between patients with major depressive disorder and healthy controls. Methods:: Blood samples were collected from 41 patients with major depressive disorder and 40 healthy age-matched controls with no history of malignancies or autoimmune disorders. The subjects were interviewed face to face according to DSM-IV diagnostic criteria. Depression score was measured using completed Beck Depression Inventory in both groups. The serum concentrations of IL-21, IL-17, and TGF-? were assessed using ELISA. Results:: The mean score of Beck Depression score in the patient and control groups was 35.4±5.5 and 11.1±2.3. IL-17 serum concentrations in the patients and the control group were 10.03±0.6 and 7.6±0.6 pg/mL, respectively (P=0.0002). TGF-? level in the patients group was significantly higher than compare to the control group; 336.7±20.19 vs. 174.8±27.20 pg/mL, (P<0.0001). However, the level of IL-21 was not statistically different between the two groups 84.30±4.57 vs. 84.12±4.15 pg/mL (P>0.05). Conclusion:: Considering pro-inflammatory cytokines, current results support the association of inflammatory response and depressive disorder. So, it seems that pro-inflammatory factors profile can be used as indicator in following of depression progress and its treatment impacts. Twit Text FOAVip Elevated IL-17 and TGF- Serum Levels: A Positive Correlation between T-helper 17 Cell-Related Pro-Inflammatory Responses with Major Depressive Disorder ????Basic Clin Neurosci http://www.kidney.de/pget.php?&tw=1&pmid=27303608 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27303608 #FOAvip English Wikipedia <ref>{{Cite pmid|27303608}}</ref> Elevated IL-17 and TGF-? Serum Levels: A Positive Correlation between T-helper 17 Cell-Related Pro-Inflammatory Responses with Major Depressive Disorder #MMPMID27303608 Davami MH; Baharlou R; Ahmadi Vasmehjani A; Ghanizadeh A; Keshtkar M; Dezhkam I; Atashzar MR Basic Clin Neurosci 2016[Apr]; 7 (2): 137-42 PMID27303608show ga Introduction:: Depression is a mental disorder that highly associated with immune system. Therefore, this study compares the serum concentrations of IL-21, IL-17, and transforming growth factor ? (TGF-?) between patients with major depressive disorder and healthy controls. Methods:: Blood samples were collected from 41 patients with major depressive disorder and 40 healthy age-matched controls with no history of malignancies or autoimmune disorders. The subjects were interviewed face to face according to DSM-IV diagnostic criteria. Depression score was measured using completed Beck Depression Inventory in both groups. The serum concentrations of IL-21, IL-17, and TGF-? were assessed using ELISA. Results:: The mean score of Beck Depression score in the patient and control groups was 35.4±5.5 and 11.1±2.3. IL-17 serum concentrations in the patients and the control group were 10.03±0.6 and 7.6±0.6 pg/mL, respectively (P=0.0002). TGF-? level in the patients group was significantly higher than compare to the control group; 336.7±20.19 vs. 174.8±27.20 pg/mL, (P<0.0001). However, the level of IL-21 was not statistically different between the two groups 84.30±4.57 vs. 84.12±4.15 pg/mL (P>0.05). Conclusion:: Considering pro-inflammatory cytokines, current results support the association of inflammatory response and depressive disorder. So, it seems that pro-inflammatory factors profile can be used as indicator in following of depression progress and its treatment impacts. äElevated IL-17 and TGF-? Serum Levels: A Positive Correlation between (epmc).pdf DeepDyve Pubget Overpricing