Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\22037591
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Lab+Chip
2011 ; 11
(24
): 4274-8
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Two-dimensional paper networks: programmable fluidic disconnects for multi-step
processes in shaped paper
#MMPMID22037591
Lutz BR
; Trinh P
; Ball C
; Fu E
; Yager P
Lab Chip
2011[Dec]; 11
(24
): 4274-8
PMID22037591
show ga
Most laboratory assays take advantage of multi-step protocols to achieve high
performance, but conventional paper-based tests (e.g., lateral flow tests) are
generally limited to assays that can be carried out in a single fluidic step. We
have developed two-dimensional paper networks (2DPNs) that use materials from
lateral flow tests but reconfigure them to enable programming of multi-step
reagent delivery sequences. The 2DPN uses multiple converging fluid inlets to
control the arrival time of each fluid to a detection zone or reaction zone, and
it requires a method to disconnect each fluid source in a corresponding timed
sequence. Here, we present a method that allows programmed disconnection of fluid
sources required for multi-step delivery. A 2DPN with legs of different lengths
is inserted into a shared buffer well, and the dropping fluid surface disconnects
each leg at in a programmable sequence. This approach could enable multi-step
laboratory assays to be converted into simple point-of-care devices that have
high performance yet remain easy to use.