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http://scihub22266oqcxt.onion/ C4891414!4891414!27347309     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Transl+Res 2016 ; 8 (5): 1998-2010 Nephropedia Template TP {{tp|p=27347309|t=2016. Clinic significance of markedly decreased ?-klothoin women with preeclampsia |pdf=|usr=}}{{27347309}} gab.com Text Clinic significance of markedly decreased -klothoin women with preeclampsia JO: Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=27347309 #FOAvip Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity and mortality. Klotho is a novel gene and the secret form, ?-klotho (?-KL), is related to preeclampsia. We conducted this cross-sectional study in Wuhan, China. We used immunohistochemistry, real-time PCR, western blot, ELISA to measure ?-KL expression in placenta and its secretion in maternal and umbilical cord serum, and analyzed correlations between ?-KL level and other parameters in normal and preeclampsia pregnancy. We found that both mRNA and protein expression of placental ?-KL in women with PE was significantly lower than that in normal pregnancy. Also, expression level of ?-KL in both maternal and umbilical cord was markedly decreased in PE patients. Further analyses showed that serum ?-KL exhibited positive association with fetal birth weight, and reverse association with oxidative stress and renal function markers. Receiver operating characteristic analysis suggested ?-KL might be a potential predictor for preeclampsia. Twit Text FOAVip Clinic significance of markedly decreased -klothoin women with preeclampsia ????Am J Transl Res http://www.kidney.de/pget.php?&tw=1&pmid=27347309 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27347309 #FOAvip English Wikipedia <ref>{{Cite pmid|27347309}}</ref> Clinic significance of markedly decreased ?-klothoin women with preeclampsia #MMPMID27347309 Fan C; Wang Y; Wang J; Lei D; Sun Y; Lei S; Hu M; Tian Y; Li R; Wang S Am J Transl Res 2016[]; 8 (5): 1998-2010 PMID27347309show ga Preeclampsia (PE) is a leading cause of maternal and perinatal morbidity and mortality. Klotho is a novel gene and the secret form, ?-klotho (?-KL), is related to preeclampsia. We conducted this cross-sectional study in Wuhan, China. We used immunohistochemistry, real-time PCR, western blot, ELISA to measure ?-KL expression in placenta and its secretion in maternal and umbilical cord serum, and analyzed correlations between ?-KL level and other parameters in normal and preeclampsia pregnancy. We found that both mRNA and protein expression of placental ?-KL in women with PE was significantly lower than that in normal pregnancy. Also, expression level of ?-KL in both maternal and umbilical cord was markedly decreased in PE patients. Further analyses showed that serum ?-KL exhibited positive association with fetal birth weight, and reverse association with oxidative stress and renal function markers. Receiver operating characteristic analysis suggested ?-KL might be a potential predictor for preeclampsia. äClinic significance of markedly decreased ?-klothoin women with preecl(epmc).pdf DeepDyve Pubget Overpricing