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Organizing pneumonia as the first manifestation of anti-synthetase syndrome #MMPMID27251562
Priyangika SMTN; karunarathna WGSG; Liyanage I; Gunawardana M; Udumalgala S; Rosa C; Kulatunga A
BMC Res Notes 2016[]; 9 (ä): ä PMID27251562show ga
Background: Anti-synthetase syndrome associated interstitial lung disease can occur either simultaneously, before, or after the development of polymyositis/dermatomyositis. Histology of interstitial lung disease can be nonspecific interstitial pneumonia, usual interstitial pneumonia, diffuse alveolar damage, organizing pneumonia. Organizing pneumonia associated anti-synthetase syndrome is a rare finding especially as the first manifestation. Case presentation: We report a 41 year old male patient who presented with organizing pneumonia and 2 years following the onset, developed polymyositis with anti-JO-1 antibody positivity. Conclusion: It is important to screen patients with organizing pneumonia for anti-synthetase syndrome which can be manifested later.