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2016 ; 44
(3
): 395-439
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Strategies to enhance rational use of antibiotics in hospital: a guideline by the
German Society for Infectious Diseases
#MMPMID27066980
de With K
; Allerberger F
; Amann S
; Apfalter P
; Brodt HR
; Eckmanns T
; Fellhauer M
; Geiss HK
; Janata O
; Krause R
; Lemmen S
; Meyer E
; Mittermayer H
; Porsche U
; Presterl E
; Reuter S
; Sinha B
; Strauß R
; Wechsler-Fördös A
; Wenisch C
; Kern WV
Infection
2016[Jun]; 44
(3
): 395-439
PMID27066980
show ga
INTRODUCTION: In the time of increasing resistance and paucity of new drug
development there is a growing need for strategies to enhance rational use of
antibiotics in German and Austrian hospitals. An evidence-based guideline on
recommendations for implementation of antibiotic stewardship (ABS) programmes was
developed by the German Society for Infectious Diseases in association with the
following societies, associations and institutions: German Society of Hospital
Pharmacists, German Society for Hygiene and Microbiology, Paul Ehrlich Society
for Chemotherapy, The Austrian Association of Hospital Pharmacists, Austrian
Society for Infectious Diseases and Tropical Medicine, Austrian Society for
Antimicrobial Chemotherapy, Robert Koch Institute. MATERIALS AND METHODS: A
structured literature research was performed in the databases EMBASE, BIOSIS,
MEDLINE and The Cochrane Library from January 2006 to November 2010 with an
update to April 2012 (MEDLINE and The Cochrane Library). The grading of
recommendations in relation to their evidence is according to the AWMF Guidance
Manual and Rules for Guideline Development. CONCLUSION: The guideline provides
the grounds for rational use of antibiotics in hospital to counteract
antimicrobial resistance and to improve the quality of care of patients with
infections by maximising clinical outcomes while minimising toxicity.
Requirements for a successful implementation of ABS programmes as well as core
and supplemental ABS strategies are outlined. The German version of the guideline
was published by the German Association of the Scientific Medical Societies
(AWMF) in December 2013.
|*Anti-Infective Agents/administration & dosage/therapeutic use
[MESH]
free
free
free
