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10.1101/gad.278887.116

http://scihub22266oqcxt.onion/10.1101/gad.278887.116
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C4888839!4888839!27198228
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suck abstract from ncbi


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pmid27198228      Genes+Dev 2016 ; 30 (10): 1187-97
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  • Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2 #MMPMID27198228
  • Schibler A; Koutelou E; Tomida J; Wilson-Pham M; Wang L; Lu Y; Cabrera AP; Chosed RJ; Li W; Li B; Shi X; Wood RD; Dent SY
  • Genes Dev 2016[May]; 30 (10): 1187-97 PMID27198228show ga
  • Schibler et al. show that both Set1 and H3K4 mutants display a benomyl resistance phenotype that requires components of the spindle assembly checkpoint (SAC), including Bub3 and Mad2. Interactions between Mad2 and H3K4 regulate resolution of the SAC by limiting closed Mad2 availability for Cdc20 inhibition.
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