Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27284425
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Mol+Clin+Oncol
2016 ; 4
(6
): 929-932
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Development of multiple malignancies following long-term glucocorticoid therapy
in a patient with leukocytoclastic vasculitis: A case report
#MMPMID27284425
Fang L
; Hu Y
; Wang W
; Hu S
; Zhang LI
; Wang R
Mol Clin Oncol
2016[Jun]; 4
(6
): 929-932
PMID27284425
show ga
Leukocytoclastic vasculitis (LCV) is a neutrophilic inflammation of the blood
vessels. LCV may present as a paraneoplastic syndrome occurring before,
synchronously with, or after the diagnosis of malignancy. In this study, we
report a unique case of multiple malignancies developing simultaneously in a
patient with a long history of LCV. The patient was originally diagnosed with LCV
and received long-term glucocorticoid treatment. After 11 years of therapy, the
patient developed three primary malignancies, including small-cell lung
carcinoma, gastric adenocarcinoma and colonic adenocarcinoma. It is likely that
LCV was not a paraneoplastic syndrome in this case, but rather an independent
process, and the development of multiple cancers is likely associated with the
long-term glucocorticoid treatment, which caused imbalance of the immune system.
Although the development of cancer during the course of glucocorticoid treatment
is very rare, clinicians must be aware of this possible association and
immunodysregulation may play a role in this context.