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suck abstract from ncbi


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pmid27274825
      Clin+Kidney+J 2016 ; 9 (3 ): 408-10
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  • Recurrent focal segmental glomerulosclerosis apparently resistant to plasmapheresis improves after surgical repair of arteriovenous fistula aneurysms #MMPMID27274825
  • Ding Y ; Francis J ; Kalish J ; Deshpande A ; Quillen K
  • Clin Kidney J 2016[Jun]; 9 (3 ): 408-10 PMID27274825 show ga
  • Focal segmental glomerulosclerosis (FSGS) is a leading cause of end-stage renal disease and has a high recurrence rate after kidney transplantation, attributed to a circulating permeability factor. Plasmapheresis is the treatment of choice after recurrence to remove the circulating factor. We present a case of recurrent FSGS 6 years after transplantation. It is instructive because proteinuria did not respond to intensive plasmapheresis-combined with rituximab-until the possibility of ineffective apheresis secondary to multiple aneurysms in the arteriovenous fistula (AVF) was considered. Proteinuria improved soon after alternative access for plasmapheresis was secured and AVF aneurysms were surgically repaired.
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