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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Cardiorenal+Med
2016 ; 6
(3
): 237-50
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Risk Factors for Acute Kidney Injury after Cardiovascular Surgery: Evidence from
2,157 Cases and 49,777 Controls - A Meta-Analysis
#MMPMID27275160
Yi Q
; Li K
; Jian Z
; Xiao YB
; Chen L
; Zhang Y
; Ma RY
Cardiorenal Med
2016[May]; 6
(3
): 237-50
PMID27275160
show ga
PURPOSE: Cardiovascular surgery-associated acute kidney injury (AKI-CS)
contributes to mortality and morbidity. However, risk factors accelerating its
development are unclear. We identified risk factors for AKI-CS in patients with
cardiopulmonary bypass in the hospital surgical intensive care unit to predict
and minimize renal complication in future cardiac surgery. METHODS: We analyzed
data from 14 case-control studies published prior to June 2014 and indexed in
Science Citation Index, PubMed, and other databases to determine the major risk
factors for AKI-CS. RESULTS: Analyzed risk factors were divided into three
groups: preoperative, intraoperative and postoperative. Preoperative factors
included: age (OR, 4.87; 95% CI, 3.50-6.24), NYHA class III/IV (OR, 2.53; 95% CI,
1.32-4.86), hypertension (OR, 1.68; 95% CI, 1.44-1.97), preoperative creatinine
(OR, 0.66; 95% CI, 0.18-1.14), peripheral vascular disease (OR, 1.31 95% CI,
1.09-1.57), respiratory system disease (OR, 1.29; 95% CI, 1.10-1.50), diabetes
mellitus (OR, 1.52; 95% CI, 1.07-2.16), and cerebrovascular disease (OR, 2.13;
95% CI, 1.11-4.09). Intraoperative factors were: cardiopulmonary bypass time (OR,
33.78; 95% CI, 23.15-44.41), aortic clamping time (OR, 13.24; 95% CI,
7.78-18.69), use of intra-aortic balloon pump (OR, 4.44; 95% CI, 2.37-8.30), and
type of surgery (OR, 1.01; 95% CI, 0.43-2.39). Postoperative factors were:
infection (OR, 3.58; 95% CI, 1.43-8.97), redo operation (OR, 2.57; 95% CI,
1.75-3.78), emergency surgery (OR, 4.76; 95% CI, 3.05-7.43), and low cardiac
output (OR, 2.30; 95% CI, 1.05-5.04). CONCLUSIONS: Our results support that
preoperative, intraoperative, and postoperative factors are associated with
AKI-CS. Ejection fraction, BMI, acute myocardial infarction, type of surgery, and
congestive heart failure were not absolutely associated with AKI.