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10.1093/database/baw089 http://scihub22266oqcxt.onion/10.1093/database/baw089 C4885605!4885605 !27242034     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27242034 &cmd=llinks): Failed to open stream: HTTP request failed! 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Abasy Atlas: a comprehensive inventory of systems, global network properties and systems-level elements across bacteria |pdf=|usr=}}{{27242034 }} gab.com Text Abasy Atlas: a comprehensive inventory of systems, global network properties and systems-level elements across bacteria JO: Database (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=27242034 #FOAvip The availability of databases electronically encoding curated regulatory networks and of high-throughput technologies and methods to discover regulatory interactions provides an invaluable source of data to understand the principles underpinning the organization and evolution of these networks responsible for cellular regulation. Nevertheless, data on these sources never goes beyond the regulon level despite the fact that regulatory networks are complex hierarchical-modular structures still challenging our understanding. This brings the necessity for an inventory of systems across a large range of organisms, a key step to rendering feasible comparative systems biology approaches. In this work, we take the first step towards a global understanding of the regulatory networks organization by making a cartography of the functional architectures of diverse bacteria. Abasy ( A: cross- BA: cteria SY: stems) Atlas provides a comprehensive inventory of annotated functional systems, global network properties and systems-level elements (global regulators, modular genes shaping functional systems, basal machinery genes and intermodular genes) predicted by the natural decomposition approach for reconstructed and meta-curated regulatory networks across a large range of bacteria, including pathogenically and biotechnologically relevant organisms. The meta-curation of regulatory datasets provides the most complete and reliable set of regulatory interactions currently available, which can even be projected into subsets by considering the force or weight of evidence supporting them or the systems that they belong to. Besides, Abasy Atlas provides data enabling large-scale comparative systems biology studies aimed at understanding the common principles and particular lifestyle adaptions of systems across bacteria. Abasy Atlas contains systems and system-level elements for 50 regulatory networks comprising 78 649 regulatory interactions covering 42 bacteria in nine taxa, containing 3708 regulons and 1776 systems. All this brings together a large corpus of data that will surely inspire studies to generate hypothesis regarding the principles governing the evolution and organization of systems and the functional architectures controlling them.Database URL: http://abasy.ccg.unam.mx. Twit Text FOAVip Abasy Atlas: a comprehensive inventory of systems, global network properties and systems-level elements across bacteria ????Database (Oxford) http://www.kidney.de/pget.php?&tw=1&pmid=27242034 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27242034 #FOAvip English Wikipedia <ref>{{Cite pmid|27242034 }}</ref> Abasy Atlas: a comprehensive inventory of systems, global network properties and systems-level elements across bacteria #MMPMID27242034 Ibarra-Arellano MA ; Campos-González AI ; Treviño-Quintanilla LG ; Tauch A ; Freyre-González JA Database (Oxford) 2016[]; 2016 (ä): ä PMID27242034 show ga The availability of databases electronically encoding curated regulatory networks and of high-throughput technologies and methods to discover regulatory interactions provides an invaluable source of data to understand the principles underpinning the organization and evolution of these networks responsible for cellular regulation. Nevertheless, data on these sources never goes beyond the regulon level despite the fact that regulatory networks are complex hierarchical-modular structures still challenging our understanding. This brings the necessity for an inventory of systems across a large range of organisms, a key step to rendering feasible comparative systems biology approaches. In this work, we take the first step towards a global understanding of the regulatory networks organization by making a cartography of the functional architectures of diverse bacteria. Abasy ( A: cross- BA: cteria SY: stems) Atlas provides a comprehensive inventory of annotated functional systems, global network properties and systems-level elements (global regulators, modular genes shaping functional systems, basal machinery genes and intermodular genes) predicted by the natural decomposition approach for reconstructed and meta-curated regulatory networks across a large range of bacteria, including pathogenically and biotechnologically relevant organisms. The meta-curation of regulatory datasets provides the most complete and reliable set of regulatory interactions currently available, which can even be projected into subsets by considering the force or weight of evidence supporting them or the systems that they belong to. Besides, Abasy Atlas provides data enabling large-scale comparative systems biology studies aimed at understanding the common principles and particular lifestyle adaptions of systems across bacteria. Abasy Atlas contains systems and system-level elements for 50 regulatory networks comprising 78 649 regulatory interactions covering 42 bacteria in nine taxa, containing 3708 regulons and 1776 systems. All this brings together a large corpus of data that will surely inspire studies to generate hypothesis regarding the principles governing the evolution and organization of systems and the functional architectures controlling them.Database URL: http://abasy.ccg.unam.mx. |*Database Management Systems [MESH] |*Databases, Genetic [MESH] |Bacteria/*genetics [MESH] |Computational Biology/*methods [MESH] |Gene Expression Regulation, Bacterial/*genetics [MESH] |Gene Regulatory Networks [MESH] |Genome, Bacterial/*genetics [MESH]Abasy Atlas: a comprehensive inventory of systems, global network prop(epmc).pdf DeepDyve Pubget Overpricing