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2016 ; 2016
(ä): ä Nephropedia Template TP
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Cytokine profile of nasal and middle ear polyps in a patient with Woakes
syndrome and eosinophilic otitis media
#MMPMID27143164
De Loof M
; De Leenheer E
; Holtappels G
; Bachert C
BMJ Case Rep
2016[May]; 2016
(ä): ä PMID27143164
show ga
Woakes' syndrome is characterised by severe recurrent nasal polyps in early
childhood with broadening of the nose, nasal dyscrinia, frontal sinus aplasia and
bronchiectasis. Eosinophilic otitis media (EOM) is an intractable condition that
can cause gradual or sudden deterioration of hearing and is associated with
comorbid asthma. For these reasons, both diseases must be recognised and treated
appropriately. We present a case of a 20-year-old man with Woakes' syndrome
complicated by EOM, with polyps in both middle ears; this condition has so far
not been described as an entity of eosinophilic disease in the literature. We
have, from reviewing the literature, learned that this is the first time that
results of tissue examination on nasal polyposis with respect to tissue IgE,
eosinophil-cationic protein, interleukin (IL)-17 and IL-5 in a patient with
Woakes' syndrome and EOM, has been reported and discussed.
|Adrenal Cortex Hormones/administration & dosage/therapeutic use
[MESH]