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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Nature 1983 ; 306 (5941): 332-6 Nephropedia Template TP
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Expression of a microinjected immunoglobulin gene in the spleen of transgenic mice #MMPMID6417544
Nature 1983[Nov]; 306 (5941): 332-6 PMID6417544show ga
Transgenic mice were produced by microinjection of a rearranged, functional immunoglobulin ? gene into fertilized mouse eggs and implantation of the microinjected embryos into foster mothers. Mice that integrated the injected gene were mated and the DNA, RNA and serum ? chains of their offspring were analysed. The data from offspring of three different transgenic mice indicate that the microinjected gene is expressed in the spleen, but not the liver of mice which inherited the injected gene.