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2016 ; 16
(5
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Xurography as a Rapid Fabrication Alternative for Point-of-Care Devices:
Assessment of Passive Micromixers
#MMPMID27196904
Martínez-López JI
; Mojica M
; Rodríguez CA
; Siller HR
Sensors (Basel)
2016[May]; 16
(5
): ä PMID27196904
show ga
Despite the copious amount of research on the design and operation of
micromixers, there are few works regarding manufacture technology aimed at
implementation beyond academic environments. This work evaluates the viability of
xurography as a rapid fabrication tool for the development of ultra-low cost
microfluidic technology for extreme Point-of-Care (POC) micromixing devices. By
eschewing photolithographic processes and the bulkiness of pumping and enclosure
systems for rapid fabrication and passively driven operation, xurography is
introduced as a manufacturing alternative for asymmetric split and recombine
(ASAR) micromixers. A T-micromixer design was used as a reference to assess the
effects of different cutting conditions and materials on the geometric features
of the resulting microdevices. Inspection by stereographic and confocal
microscopy showed that it is possible to manufacture devices with less than 8%
absolute dimensional error. Implementation of the manufacturing methodology in
modified circular shape- based SAR microdevices (balanced and unbalanced
configurations) showed that, despite the precision limitations of the xurographic
process, it is possible to implement this methodology to produce functional
micromixing devices. Mixing efficiency was evaluated numerically and
experimentally at the outlet of the microdevices with performances up to 40%.
Overall, the assessment encourages further research of xurography for the
development of POC micromixers.