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10.1038/nrg3604

http://scihub22266oqcxt.onion/10.1038/nrg3604
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C4882605!4882605!24052086
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suck abstract from ncbi


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pmid24052086      Nat+Rev+Genet 2013 ; 14 (10): 692-702
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  • Recent human adaptation: genomic approaches, interpretation and insights #MMPMID24052086
  • Scheinfeldt LB; Tishkoff SA
  • Nat Rev Genet 2013[Oct]; 14 (10): 692-702 PMID24052086show ga
  • The recent availability of genomic data has spurred many genome-wide studies of human adaptation in different populations worldwide. Such studies have provided insights into novel candidate genes and pathways that are putatively involved in adaptation to different environments, diets and disease prevalence. However, much work is needed to translate these results into candidate adaptive variants that are biologically interpretable. In this Review, we discuss methods that may help to identify true biological signals of selection and studies that incorporate complementary phenotypic and functional data. We conclude with recommendations for future studies that focus on opportunities to use integrative genomics methodologies in human adaptation studies.
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