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10.3390/jcm5050051 http://scihub22266oqcxt.onion/10.3390/jcm5050051 C4882480!4882480!27136592     free     free     free       J+Clin+Med 2016 ; 5 (5): ä Nephropedia Template TP {{tp|p=27136592|t=2016. Tumor Budding: The Name is EMT Partial EMT |pdf=|usr=}}{{27136592}} gab.com Text Tumor Budding: The Name is EMT Partial EMT JO: J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=27136592 #FOAvip Tumor budding is a histological phenomenon encountered in various cancers, whereby individual malignant cells and/or small clusters of malignant cells are seen in the tumor stroma. Postulated to be mirror epithelial-mesenchymal transition, tumor budding has been associated with poor cancer outcomes. However, the vast heterogeneity in its exact definition, methodology of assessment, and patient stratification need to be resolved before it can be routinely used as a standardized prognostic feature. Here, we discuss the heterogeneity in defining and assessing tumor budding, its clinical significance across multiple cancer types, and its prospective implementation in clinical practice. Next, we review the emerging evidence about partial, rather than complete, epithelial-mesenchymal phenotype at the tumor bud level, and its connection with tumor proliferation, quiescence, and stemness. Finally, based on recent literature, indicating a co-expression of epithelial and mesenchymal markers in many tumor buds, we posit tumor budding to be a manifestation of this hybrid epithelial/mesenchymal phenotype displaying collective cell migration. Twit Text FOAVip Tumor Budding: The Name is EMT Partial EMT ????J Clin Med http://www.kidney.de/pget.php?&tw=1&pmid=27136592 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27136592 #FOAvip English Wikipedia <ref>{{Cite pmid|27136592}}</ref> Tumor Budding: The Name is EMT Partial EMT #MMPMID27136592 Grigore AD; Jolly MK; Jia D; Farach-Carson MC; Levine H J Clin Med 2016[May]; 5 (5): ä PMID27136592show ga Tumor budding is a histological phenomenon encountered in various cancers, whereby individual malignant cells and/or small clusters of malignant cells are seen in the tumor stroma. Postulated to be mirror epithelial-mesenchymal transition, tumor budding has been associated with poor cancer outcomes. However, the vast heterogeneity in its exact definition, methodology of assessment, and patient stratification need to be resolved before it can be routinely used as a standardized prognostic feature. Here, we discuss the heterogeneity in defining and assessing tumor budding, its clinical significance across multiple cancer types, and its prospective implementation in clinical practice. Next, we review the emerging evidence about partial, rather than complete, epithelial-mesenchymal phenotype at the tumor bud level, and its connection with tumor proliferation, quiescence, and stemness. Finally, based on recent literature, indicating a co-expression of epithelial and mesenchymal markers in many tumor buds, we posit tumor budding to be a manifestation of this hybrid epithelial/mesenchymal phenotype displaying collective cell migration. äTumor Budding: The Name is EMT Partial EMT (epmc).pdf DeepDyve Pubget Overpricing