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10.1159/000439595 http://scihub22266oqcxt.onion/10.1159/000439595 C4881269!4881269!27239462     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ocul+Oncol+Pathol 2016 ; 2 (3): 181-4 Nephropedia Template TP {{tp|p=27239462|t=2016. Late Presentation of Retinoblastoma in a Teen with Aicardi Syndrome |pdf=|usr=}}{{27239462}} gab.com Text Late Presentation of Retinoblastoma in a Teen with Aicardi Syndrome JO: Ocul Oncol Pathol http://www.kidney.de/pget.php?&tw=1&pmid=27239462 #FOAvip Background/Aims: Retinoblastoma (Rb) generally presents in children <8 years of age. Aicardi syndrome (AS) is a congenital, neurodevelopmental disorder that has been associated with various ophthalmic abnormalities, but no reports have related it to a delayed presentation of Rb. This report describes the late presentation of Rb in a teenage patient with AS and suggests modifications in ophthalmic screening to facilitate early detection. Methods: A chart review was conducted of a patient with AS. We examined the ophthalmic history, fundus images and B-scan ultrasonography. Histopathological analysis was conducted on globe sections. Results: The patient's ophthalmic history was consistent with normal findings of AS: fundus images and B-scan ultrasonography revealed chorioretinal lacunae and an area of retinal detachment, respectively. The patient presented with chronic irritation and mydriasis of the blind left eye. This was enucleated as treatment. Histopathology revealed a focally differentiated Rb. Immunohistochemistry demonstrated that the tumor cells were positive for synaptophysin and negative for the wild-type Rb protein, and a high Ki-67 proliferation index was shown. Conclusion: Our patient was diagnosed with Rb at age 16. AS has been associated with numerous ophthalmic findings, but this is the first report relating it to a late Rb presentation. Meticulous ophthalmic examinations should be considered through the teenage years and early adulthood of AS patients. Twit Text FOAVip Late Presentation of Retinoblastoma in a Teen with Aicardi Syndrome ????Ocul Oncol Pathol http://www.kidney.de/pget.php?&tw=1&pmid=27239462 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27239462 #FOAvip English Wikipedia <ref>{{Cite pmid|27239462}}</ref> Late Presentation of Retinoblastoma in a Teen with Aicardi Syndrome #MMPMID27239462 Akinfenwa PY; Chévez-Barrios P; Harper CA; Gombos DS Ocul Oncol Pathol 2016[Apr]; 2 (3): 181-4 PMID27239462show ga Background/Aims: Retinoblastoma (Rb) generally presents in children <8 years of age. Aicardi syndrome (AS) is a congenital, neurodevelopmental disorder that has been associated with various ophthalmic abnormalities, but no reports have related it to a delayed presentation of Rb. This report describes the late presentation of Rb in a teenage patient with AS and suggests modifications in ophthalmic screening to facilitate early detection. Methods: A chart review was conducted of a patient with AS. We examined the ophthalmic history, fundus images and B-scan ultrasonography. Histopathological analysis was conducted on globe sections. Results: The patient's ophthalmic history was consistent with normal findings of AS: fundus images and B-scan ultrasonography revealed chorioretinal lacunae and an area of retinal detachment, respectively. The patient presented with chronic irritation and mydriasis of the blind left eye. This was enucleated as treatment. Histopathology revealed a focally differentiated Rb. Immunohistochemistry demonstrated that the tumor cells were positive for synaptophysin and negative for the wild-type Rb protein, and a high Ki-67 proliferation index was shown. Conclusion: Our patient was diagnosed with Rb at age 16. AS has been associated with numerous ophthalmic findings, but this is the first report relating it to a late Rb presentation. Meticulous ophthalmic examinations should be considered through the teenage years and early adulthood of AS patients. äLate Presentation of Retinoblastoma in a Teen with Aicardi Syndrome (epmc).pdf DeepDyve Pubget Overpricing