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2015 ; 27
(3-4
): 132-5
Nephropedia Template TP
gab.com Text
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English Wikipedia
Diabetes mellitus, diabetes insipidus, optic atrophy, and deafness: A case of
Wolfram (DIDMOAD) syndrome
#MMPMID27239592
Maleki N
; Bashardoust B
; Zakeri A
; Salehifar A
; Tavosi Z
J Curr Ophthalmol
2015[Sep]; 27
(3-4
): 132-5
PMID27239592
show ga
PURPOSE: To report a case of Wolfram syndrome (WS) characterized by diabetes
mellitus, diabetes insipidus, progressive optic atrophy, and deafness. CASE
REPORT: A 19-year-old female patient, a known case of diabetes mellitus type I
from six years before, presented with progressive vision loss since four years
earlier. On fundoscopic examination, she had bilateral optic atrophy without
diabetic retinopathy. The patient also had diabetes insipidus, neurosensory
deafness, and neurogenic bladder. CONCLUSION: WS should be considered a
differential diagnosis in patients with diabetes mellitus who present with optic
atrophy, and it is necessary to perform a hearing test as well as collecting 24-h
urine output.