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10.1186/s13014-016-0651-5

http://scihub22266oqcxt.onion/10.1186/s13014-016-0651-5
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suck abstract from ncbi


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pmid27229710      Radiat+Oncol 2016 ; 11 (ä): ä
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  • Renal atrophy after stereotactic body radiotherapy for renal cell carcinoma #MMPMID27229710
  • Yamamoto T; Kadoya N; Takeda K; Matsushita H; Umezawa R; Sato K; Kubozono M; Ito K; Ishikawa Y; Kozumi M; Takahashi N; Katagiri Y; Onishi H; Jingu K
  • Radiat Oncol 2016[]; 11 (ä): ä PMID27229710show ga
  • Background: Renal atrophy is observed in an irradiated kidney. The aim of this study was to determine dose-volume histogram parameters and other factors that predict renal atrophy after 10-fraction stereotactic body radiotherapy (SBRT) for primary renal cell carcinoma (RCC). Methods: A total of 14 patients (11 males, 3 females) who received SBRT for RCC at Tohoku University Hospital between April 2010 and February 2014 were analyzed. The median serum creatinine level was 1.1 mg/dl and two patients had a single kidney. Nine patients were implanted with fiducial markers. The median tumor diameter was 30 mm. SBRT was delivered at 70 Gy in 10 fractions for 7 tumors, at 60 Gy in 10 fractions for 2 tumors, and at 50 Gy in 10 fractions for 5 tumors with 6 and/or 15 MV X-ray using 5 to 8 multi-static beams. Renal atrophy was assessed using post-SBRT CT images after 12?24 months intervals. Correlations were examined by Spearman rank correlation analysis. Differences between two groups were evaluated by the Mann-Whitney test, and pairwise comparisons were made by the Wilcoxon signed-rank test. Results: The median tumor volume shrunk from 14.8 cc to 10.6 cc (p?=?0.12), and the median irradiated kidney volume changed from 160.4 cc to 137.1 cc (p?
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