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10.1586/1744666X.2015.1083861 http://scihub22266oqcxt.onion/10.1586/1744666X.2015.1083861 C4879962!4879962!26548357     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Expert+Rev+Clin+Immunol 2015 ; 11 (12): 1379-90 Nephropedia Template TP {{tp|p=26548357|t=2015. Recent Advances in Understanding Xenotransplantation: Implications for the Clinic |pdf=|usr=}}{{26548357}} gab.com Text Recent Advances in Understanding Xenotransplantation: Implications for the Clinic JO: Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26548357 #FOAvip The results of organ and cell allotransplantation continue to improve, but the field remains limited by a lack of deceased donor organs. Xenotransplantation, e.g., between pig and human, offers unlimited organs and cells for clinical transplantation. The immune barriers include a strong innate immune response in addition to the adaptive T cell response. The innate response has largely been overcome by the transplantation of organs from pigs with genetic modifications that protect their tissues from this response. T cell-mediated rejection can be controlled by immunosuppressive agents that inhibit costimulation. Coagulation dysfunction between the pig and primate remains problematic but is being overcome by the transplantation of organs from pigs that express human coagulation-regulatory proteins. The remaining barriers will be resolved by the introduction of novel genetically-engineered pigs. Limited clinical trials of pig islet and corneal transplantation are already underway. Twit Text FOAVip Recent Advances in Understanding Xenotransplantation: Implications for the Clinic ????Expert Rev Clin Immunol http://www.kidney.de/pget.php?&tw=1&pmid=26548357 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26548357 #FOAvip English Wikipedia <ref>{{Cite pmid|26548357}}</ref> Recent Advances in Understanding Xenotransplantation: Implications for the Clinic #MMPMID26548357 Cooper DKC; Bottino R Expert Rev Clin Immunol 2015[]; 11 (12): 1379-90 PMID26548357show ga The results of organ and cell allotransplantation continue to improve, but the field remains limited by a lack of deceased donor organs. Xenotransplantation, e.g., between pig and human, offers unlimited organs and cells for clinical transplantation. The immune barriers include a strong innate immune response in addition to the adaptive T cell response. The innate response has largely been overcome by the transplantation of organs from pigs with genetic modifications that protect their tissues from this response. T cell-mediated rejection can be controlled by immunosuppressive agents that inhibit costimulation. Coagulation dysfunction between the pig and primate remains problematic but is being overcome by the transplantation of organs from pigs that express human coagulation-regulatory proteins. The remaining barriers will be resolved by the introduction of novel genetically-engineered pigs. Limited clinical trials of pig islet and corneal transplantation are already underway. äRecent Advances in Understanding Xenotransplantation: Implications for(epmc).pdf DeepDyve Pubget Overpricing