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2016 ; 25
(2
): 125-9
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Psychotic Symptoms in a Child with Long Standing SLE Nephritis: Neuropsychiatric
Manifestation or Sequelae to Lupus?
#MMPMID27274749
Mahapatra A
; Sharma P
; Sagar R
J Can Acad Child Adolesc Psychiatry
2016[Spr]; 25
(2
): 125-9
PMID27274749
show ga
Systemic Lupus Erythematosus (SLE) is a prototypic autoimmune disease of unknown
etiology, which affects multiple organ systems including the central nervous
system (CNS). Though not common, childhood onset SLE is a known and established
entity. Neuropsychiatric symptoms are common in childhood onset SLE. Of these,
psychosis and behavioural symptoms are relatively rare, and there is no consensus
on the proper treatment of such cases. We report a case of 13-year-old boy,
diagnosed with lupus nephritis, and presented with psychosis and behavioural
symptoms. The highlight of this case is that the psychiatric symptoms were
present despite the primary illness being quiescent. Thus, the patient was
treated with Olanzapine and lorazepam, while continuing immunosuppressive therapy
as previously. Also, MRI brain revealed vasculitic changes in the right
hemisphere, which might be one of the etiological factors playing role in the
development of these neuropsychiatric symptoms.