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10.12688/f1000research.7574.1 http://scihub22266oqcxt.onion/10.12688/f1000research.7574.1 C4879934!4879934!27239294     free     free     free       F1000Res 2016 ; 5 (ä): ä Nephropedia Template TP {{tp|p=27239294|t=2016. Toxic epidermal necrolysis |pdf=|usr=}}{{27239294}} gab.com Text Toxic epidermal necrolysis JO: F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=27239294 #FOAvip Toxic epidermal necrolysis (TEN) is a rare, life-threatening drug-induced skin disease with a mortality rate of approximately 30%. The clinical hallmark of TEN is a marked skin detachment caused by extensive keratinocyte cell death associated with mucosal involvement. The exact pathogenic mechanism of TEN is still uncertain. Recent advances in this field have led to the identification of several factors that might contribute to the induction of excessive apoptosis of keratinocytes. In addition, specific human leukocyte antigen types seem to be associated with certain drugs and the development of TEN. As well-controlled studies are lacking, patients are treated with various immunomodulators (e.g. intravenous immunoglobulin) in addition to the best supportive care. Twit Text FOAVip Toxic epidermal necrolysis ????F1000Res http://www.kidney.de/pget.php?&tw=1&pmid=27239294 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27239294 #FOAvip English Wikipedia <ref>{{Cite pmid|27239294}}</ref> Toxic epidermal necrolysis #MMPMID27239294 Hoetzenecker W; Mehra T; Saulite I; Glatz M; Schmid-Grendelmeier P; Guenova E; Cozzio A; French LE F1000Res 2016[]; 5 (ä): ä PMID27239294show ga Toxic epidermal necrolysis (TEN) is a rare, life-threatening drug-induced skin disease with a mortality rate of approximately 30%. The clinical hallmark of TEN is a marked skin detachment caused by extensive keratinocyte cell death associated with mucosal involvement. The exact pathogenic mechanism of TEN is still uncertain. Recent advances in this field have led to the identification of several factors that might contribute to the induction of excessive apoptosis of keratinocytes. In addition, specific human leukocyte antigen types seem to be associated with certain drugs and the development of TEN. As well-controlled studies are lacking, patients are treated with various immunomodulators (e.g. intravenous immunoglobulin) in addition to the best supportive care. äToxic epidermal necrolysis (epmc).pdf DeepDyve Pubget Overpricing