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10.1038/mp.2015.172 http://scihub22266oqcxt.onion/10.1038/mp.2015.172 C4879118!4879118 !26598068     free     free     free Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 259.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26598068 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mol+Psychiatry 2016 ; 21 (10 ): 1434-40 Nephropedia Template TP {{tp|p=26598068 |t=2016. Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate |pdf=|usr=}}{{26598068 }} gab.com Text Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate JO: Mol Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=26598068 #FOAvip Attention-deficit/hyperactivity disorder (ADHD) is a heritable, chronic, neurodevelopmental disorder with serious long-term repercussions. Despite being one of the most common cognitive disorders, the clinical diagnosis of ADHD is based on subjective assessments of perceived behaviors. Endophenotypes (neurobiological markers that cosegregate and are associated with an illness) are thought to provide a more powerful and objective framework for revealing the underlying neurobiology than syndromic psychiatric classification. Here, we present the results of applying genetic linkage and association analyses to neuropsychological endophenotypes using microsatellite and single nucleotide polymorphisms. We found several new genetic regions linked and/or associated with these endophenotypes, and others previously associated to ADHD, for example, loci harbored in the LPHN3, FGF1, POLR2A, CHRNA4 and ANKFY1 genes. These findings, when compared with those linked and/or associated to ADHD, suggest that these endophenotypes lie on shared pathways. The genetic information provided by this study offers a novel and complementary method of assessing the genetic causes underpinning the susceptibility to behavioral conditions and may offer new insights on the neurobiology of the disorder. Twit Text FOAVip Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate ????Mol Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=26598068 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26598068 #FOAvip English Wikipedia <ref>{{Cite pmid|26598068 }}</ref> Linkage and association analysis of ADHD endophenotypes in extended and multigenerational pedigrees from a genetic isolate #MMPMID26598068 Mastronardi CA ; Pillai E ; Pineda DA ; Martinez AF ; Lopera F ; Velez JI ; Palacio JD ; Patel H ; Easteal S ; Acosta MT ; Castellanos FX ; Muenke M ; Arcos-Burgos M Mol Psychiatry 2016[Oct]; 21 (10 ): 1434-40 PMID26598068 show ga Attention-deficit/hyperactivity disorder (ADHD) is a heritable, chronic, neurodevelopmental disorder with serious long-term repercussions. Despite being one of the most common cognitive disorders, the clinical diagnosis of ADHD is based on subjective assessments of perceived behaviors. Endophenotypes (neurobiological markers that cosegregate and are associated with an illness) are thought to provide a more powerful and objective framework for revealing the underlying neurobiology than syndromic psychiatric classification. Here, we present the results of applying genetic linkage and association analyses to neuropsychological endophenotypes using microsatellite and single nucleotide polymorphisms. We found several new genetic regions linked and/or associated with these endophenotypes, and others previously associated to ADHD, for example, loci harbored in the LPHN3, FGF1, POLR2A, CHRNA4 and ANKFY1 genes. These findings, when compared with those linked and/or associated to ADHD, suggest that these endophenotypes lie on shared pathways. The genetic information provided by this study offers a novel and complementary method of assessing the genetic causes underpinning the susceptibility to behavioral conditions and may offer new insights on the neurobiology of the disorder. |Adolescent [MESH] |Adult [MESH] |Aged [MESH] |Aged, 80 and over [MESH] |Attention Deficit Disorder with Hyperactivity/*genetics [MESH] |Child [MESH] |Cognition Disorders/genetics [MESH] |Colombia [MESH] |Endophenotypes/*analysis [MESH] |Ethnicity/genetics [MESH] |Female [MESH] |Genetic Association Studies/methods [MESH] |Genetic Linkage/genetics [MESH] |Genetic Predisposition to Disease/genetics/psychology [MESH] |Humans [MESH] |Male [MESH] |Microsatellite Repeats/genetics [MESH] |Middle Aged [MESH] |Neuropsychological Tests [MESH] |Pedigree [MESH]Linkage and association analysis of ADHD endophenotypes in extended an(epmc).pdf DeepDyve Pubget Overpricing