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2015 ; 27
(1-2
): 12-5
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Pseudoexfoliation syndrome: Effect of phacoemulsification on intraocular pressure
and its diurnal variation
#MMPMID27239568
Vahedian Z
; Salmanroghani R
; Fakhraie G
; Moghimi S
; Eslami Y
; Zarei R
; Mohammadi M
J Curr Ophthalmol
2015[Mar]; 27
(1-2
): 12-5
PMID27239568
show ga
PURPOSE: To evaluate the effect of phacoemulsification on intraocular pressure
(IOP) in pseudoexfoliation (PEX) syndrome and its diurnal variation. METHODS: In
this prospective, non-comparative, interventional case series,
phacoemulsification was done for patients with PEX and concomitant visually
significant cataract. Follow-up examinations including IOP measurement were done
at postoperative day 1, week 1, month 1, month 3, and month 6. All IOP
measurements were performed twice daily: once in the morning between 8 and 10 AM
and the other in the evening between 6 and 8 PM. The minimum and maximum IOP and
the mean IOP were recorded. IOP variation was defined as the difference between
maximum and minimum pressures. RESULTS: Sixty-eight eyes of 68 patients were
analyzed. The mean IOP dropped from 17.45 ± 3.32 mm Hg to 12.57 ± 1.58 mm Hg at 6
months. The minimum and maximum IOP dropped from 14.97 ± 3.46 mm Hg and 20.03 ±
3.39 to 11.53 ± 1.79 mm Hg and 13.01 ± 1.81 after 6 months, respectively. Diurnal
IOP variation dropped from 5.06 ± 1.85 mm Hg (range 2-10) at baseline to 1.49 ±
0.93 mm Hg (range 0-4) at postoperative month 6 (p < 0.001 for all). This drop
was not correlated with age and CCT, but was strongly correlated with baseline
IOP variation (r = 0.847, p < 0.001). CONCLUSION: Phacoemulsification without any
additional intervention can be an attractive choice in managing the IOP and its
diurnal variations in pseudoexfoliation patients, even with elevated IOP, who do
not have advanced optic nerve damage.