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10.1002/pbc.25970 http://scihub22266oqcxt.onion/10.1002/pbc.25970 C4877189!4877189 !26990031     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=26990031 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26990031 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Pediatr+Blood+Cancer 2016 ; 63 (7 ): 1163-7 Nephropedia Template TP {{tp|p=26990031 |t=2016. Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma |pdf=|usr=}}{{26990031 }} gab.com Text Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma JO: Pediatr Blood Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26990031 #FOAvip Fibrolamellar hepatocellular carcinoma (FL-HCC) has historically been classified as a rare subtype of HCC. However, unlike "classic" HCC, it occurs in children and young adults without underlying liver disease. The recent discovery of a deletion mutation in all FL-HCCs represented a major advancement in understanding the pathogenesis of this disease. This deletion results in the fusion of the genes encoding a heat shock protein (DNAJB1) and the catalytic subunit of protein kinase A (PKA, PRKACA), and overexpression of PRKACA and enhanced cAMP-dependent PKA activity. This review summarizes recent advancements in FL-HCC pathogenesis and characteristics of the HSP40-PKA C protein. Twit Text FOAVip Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma ????Pediatr Blood Cancer http://www.kidney.de/pget.php?&tw=1&pmid=26990031 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26990031 #FOAvip English Wikipedia <ref>{{Cite pmid|26990031 }}</ref> Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From Adult Hepatocellular Carcinoma #MMPMID26990031 Riggle KM ; Turnham R ; Scott JD ; Yeung RS ; Riehle KJ Pediatr Blood Cancer 2016[Jul]; 63 (7 ): 1163-7 PMID26990031 show ga Fibrolamellar hepatocellular carcinoma (FL-HCC) has historically been classified as a rare subtype of HCC. However, unlike "classic" HCC, it occurs in children and young adults without underlying liver disease. The recent discovery of a deletion mutation in all FL-HCCs represented a major advancement in understanding the pathogenesis of this disease. This deletion results in the fusion of the genes encoding a heat shock protein (DNAJB1) and the catalytic subunit of protein kinase A (PKA, PRKACA), and overexpression of PRKACA and enhanced cAMP-dependent PKA activity. This review summarizes recent advancements in FL-HCC pathogenesis and characteristics of the HSP40-PKA C protein. |*Base Sequence [MESH] |*Sequence Deletion [MESH] |Adolescent [MESH] |Adult [MESH] |Carcinoma, Hepatocellular/classification/*genetics/pathology [MESH] |Child [MESH] |Child, Preschool [MESH] |Cyclic AMP-Dependent Protein Kinase Catalytic Subunits/*genetics [MESH] |Female [MESH] |HSP40 Heat-Shock Proteins/*genetics [MESH] |Humans [MESH] |Liver Neoplasms/classification/*genetics/pathology [MESH] |Male [MESH]Fibrolamellar Hepatocellular Carcinoma: Mechanistic Distinction From A(epmc).pdf DeepDyve Pubget Overpricing