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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Neurosurg+Pediatr
2016 ; 17
(5
): 525-32
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Chiari malformation Type I surgery in pediatric patients Part 2: complications
and the influence of comorbid disease in California, Florida, and New York
#MMPMID26799408
Greenberg JK
; Olsen MA
; Yarbrough CK
; Ladner TR
; Shannon CN
; Piccirillo JF
; Anderson RC
; Wellons JC 3rd
; Smyth MD
; Park TS
; Limbrick DD Jr
J Neurosurg Pediatr
2016[May]; 17
(5
): 525-32
PMID26799408
show ga
OBJECTIVE Chiari malformation Type I (CM-I) is a common and often debilitating
pediatric neurological disease. However, efforts to guide preoperative counseling
and improve outcomes research are impeded by reliance on small, single-center
studies. Consequently, the objective of this study was to investigate CM-I
surgical outcomes using population-level administrative billing data. METHODS The
authors used Healthcare Cost and Utilization Project State Inpatient Databases
(SID) to study pediatric patients undergoing surgical decompression for CM-I from
2004 to 2010 in California, Florida, and New York. They assessed the prevalence
and influence of preoperative complex chronic conditions (CCC) among included
patients. Outcomes included medical and surgical complications within 90 days of
treatment. Multivariate logistic regression was used to identify risk factors for
surgical complications. RESULTS A total of 936 pediatric CM-I surgeries were
identified for the study period. Overall, 29.2% of patients were diagnosed with
syringomyelia and 13.7% were diagnosed with scoliosis. Aside from syringomyelia
and scoliosis, 30.3% of patients had at least 1 CCC, most commonly neuromuscular
(15.2%) or congenital or genetic (8.4%) disease. Medical complications were
uncommon, occurring in 2.6% of patients. By comparison, surgical complications
were diagnosed in 12.7% of patients and typically included shunt-related
complications (4.0%), meningitis (3.7%), and other neurosurgery-specific
complications (7.4%). Major complications (e.g., stroke or myocardial infarction)
occurred in 1.4% of patients. Among children with CCCs, only comorbid
hydrocephalus was associated with a significantly increased risk of surgical
complications (OR 4.5, 95% CI 2.5-8.1). CONCLUSIONS Approximately 1 in 8
pediatric CM-I patients experienced a surgical complication, whereas medical
complications were rare. Although CCCs were common in pediatric CM-I patients,
only hydrocephalus was independently associated with increased risk of surgical
events. These results may inform patient counseling and guide future research
efforts.