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10.1007/s13238-011-1100-8 http://scihub22266oqcxt.onion/10.1007/s13238-011-1100-8 C4875270!4875270 !21976058     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=21976058 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Protein+Cell 2011 ; 2 (9 ): 691-5 Nephropedia Template TP {{tp|p=21976058 |t=2011. Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention |pdf=|usr=}}{{21976058 }} gab.com Text Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention JO: Protein Cell http://www.kidney.de/pget.php?&tw=1&pmid=21976058 #FOAvip Biotin is an important micronutrient that serves as an essential enzyme cofactor. Bacteria obtain biotin either through de novo synthesis or by active uptake from exogenous sources. Mycobacteria are unusual amongst bacteria in that their primary source of biotin is through de novo synthesis. Here we review the importance of biotin biosynthesis in the lifecycle of Mycobacteria. Genetic screens designed to identify key metabolic processes have highlighted a role for the biotin biosynthesis in bacilli growth, infection and survival during the latency phase. These studies help to establish the biotin biosynthetic pathway as a potential drug target for new anti-tuberculosis agents. Twit Text FOAVip Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention ????Protein Cell http://www.kidney.de/pget.php?&tw=1&pmid=21976058 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21976058 #FOAvip English Wikipedia <ref>{{Cite pmid|21976058 }}</ref> Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochemistry and molecular intervention #MMPMID21976058 Salaemae W ; Azhar A ; Booker GW ; Polyak SW Protein Cell 2011[Sep]; 2 (9 ): 691-5 PMID21976058 show ga Biotin is an important micronutrient that serves as an essential enzyme cofactor. Bacteria obtain biotin either through de novo synthesis or by active uptake from exogenous sources. Mycobacteria are unusual amongst bacteria in that their primary source of biotin is through de novo synthesis. Here we review the importance of biotin biosynthesis in the lifecycle of Mycobacteria. Genetic screens designed to identify key metabolic processes have highlighted a role for the biotin biosynthesis in bacilli growth, infection and survival during the latency phase. These studies help to establish the biotin biosynthetic pathway as a potential drug target for new anti-tuberculosis agents. |*Genome, Bacterial [MESH] |Biotin/*biosynthesis [MESH] |Carbon-Carbon Ligases/metabolism [MESH] |Carrier Proteins/metabolism [MESH] |Cell Membrane/metabolism [MESH] |Coenzymes/metabolism [MESH] |Fatty Acids/biosynthesis [MESH] |Genes, Bacterial [MESH] |Metabolic Networks and Pathways [MESH] |Molecular Structure [MESH] |Mycobacterium Infections/microbiology [MESH] |Mycobacterium tuberculosis/genetics/metabolism/pathogenicity/*physiology [MESH]Biotin biosynthesis in Mycobacterium tuberculosis: physiology, biochem(epmc).pdf DeepDyve Pubget Overpricing