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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Comput+Struct+Biotechnol+J 2016 ; 14 (ä): 87-90 Nephropedia Template TP
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Common integration sites of published datasets identified using a graph-based framework #MMPMID27257471
Vasciaveo A; Velevska I; Politano G; Savino A; Schmidt M; Fronza R
Comput Struct Biotechnol J 2016[]; 14 (ä): 87-90 PMID27257471show ga
With next-generation sequencing, the genomic data available for the characterization of integration sites (IS) has dramatically increased. At present, in a single experiment, several thousand viral integration genome targets can be investigated to define genomic hot spots. In a previous article, we renovated a formal CIS analysis based on a rigid fixed window demarcation into a more stretchy definition grounded on graphs. Here, we present a selection of supporting data related to the graph-based framework (GBF) from our previous article, in which a collection of common integration sites (CIS) was identified on six published datasets. In this work, we will focus on two datasets, ISRTCGD and ISHIV, which have been previously discussed. Moreover, we show in more detail the workflow design that originates the datasets.