Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27239328
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27239328
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMJ+Open+Gastroenterol
2016 ; 3
(1
): e000087
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Faecal microbiota transplantation: applications and limitations in treating
gastrointestinal disorders
#MMPMID27239328
Sbahi H
; Di Palma JA
BMJ Open Gastroenterol
2016[]; 3
(1
): e000087
PMID27239328
show ga
The process of stool transfer from healthy donors to the sick, known as faecal
microbiota transplantation (FMT), has an ancient history. However, only recently
researchers started investigating its applications in an evidence-based manner.
Current knowledge of the microbiome, the concept of dysbiosis and results of
preliminary research suggest that there is an association between
gastrointestinal bacterial disruption and certain disorders. Researchers have
studied the effects of FMT on various gastrointestinal and non-gastrointestinal
diseases, but have been unable to precisely pinpoint specific bacterial strains
responsible for the observed clinical improvement or futility of the process. The
strongest available data support the efficacy of FMT in the treatment of
recurrent Clostridium difficile infection with cure rates reported as high as 90%
in clinical trials. The use of FMT in other conditions including inflammatory
bowel disease, functional gastrointestinal disorders, obesity and metabolic
syndrome is still controversial. Results from clinical studies are conflicting,
which reflects the gap in our knowledge of the microbiome composition and
function, and highlights the need for a more defined and personalised microbial
isolation and transfer.