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10.1038/srep26401 http://scihub22266oqcxt.onion/10.1038/srep26401 C4873791!4873791 !27198619     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27198619 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27198619 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Sci+Rep 2016 ; 6 (ä): 26401 Nephropedia Template TP {{tp|p=27198619 |t=2016. Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins |pdf=|usr=}}{{27198619 }} gab.com Text Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27198619 #FOAvip A novel computational approach of coevolution analysis allowed us to reconstruct the protein-protein interaction network of the Hepatitis C Virus (HCV) at the residue resolution. For the first time, coevolution analysis of an entire viral genome was realized, based on a limited set of protein sequences with high sequence identity within genotypes. The identified coevolving residues constitute highly relevant predictions of protein-protein interactions for further experimental identification of HCV protein complexes. The method can be used to analyse other viral genomes and to predict the associated protein interaction networks. Twit Text FOAVip Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=27198619 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27198619 #FOAvip English Wikipedia <ref>{{Cite pmid|27198619 }}</ref> Coevolution analysis of Hepatitis C virus genome to identify the structural and functional dependency network of viral proteins #MMPMID27198619 Champeimont R ; Laine E ; Hu SW ; Penin F ; Carbone A Sci Rep 2016[May]; 6 (ä): 26401 PMID27198619 show ga A novel computational approach of coevolution analysis allowed us to reconstruct the protein-protein interaction network of the Hepatitis C Virus (HCV) at the residue resolution. For the first time, coevolution analysis of an entire viral genome was realized, based on a limited set of protein sequences with high sequence identity within genotypes. The identified coevolving residues constitute highly relevant predictions of protein-protein interactions for further experimental identification of HCV protein complexes. The method can be used to analyse other viral genomes and to predict the associated protein interaction networks. |Base Sequence [MESH] |Binding Sites [MESH] |Computational Biology/*methods [MESH] |Evolution, Molecular [MESH] |Genome, Viral [MESH] |Genotype [MESH] |Hepacivirus/chemistry/*genetics/metabolism [MESH] |Models, Molecular [MESH] |Protein Binding [MESH] |Protein Interaction Maps [MESH]Coevolution analysis of Hepatitis C virus genome to identify the struc(epmc).pdf DeepDyve Pubget Overpricing