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A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

http://scihub22266oqcxt.onion/ C4872554!4872554 !27232238     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27232238 &cmd=llinks): Failed to open stream: HTTP request failed! 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Quelques chiffres derrière la décision du Canada d'adopter une politique sur les médicaments orphelins: approbations pour les médicaments orphelins des États-Unis, 1997-2012 |pdf=|usr=}}{{27232238 }} gab.com Text Quelques chiffres derrière la décision du Canada d'adopter une politique sur les médicaments orphelins: approbations pour les médicaments orphelins des États-Unis, 1997-2012 JO: Healthc Policy http://www.kidney.de/pget.php?&tw=1&pmid=27232238 #FOAvip We examined whether access to US-approved orphan drugs in Canada has changed between 1997 (when Canada chose not to adopt an orphan drug policy) and 2012 (when Canada reversed its policy decision). Specifically, we looked at two dimensions of access to US-approved orphan drugs in Canada: (1) regulatory access; and (2) temporal access. Whereas only 63% of US-approved orphan drugs were granted regulatory approval in 1997, we found that regulatory access to US-approved orphan drugs in Canada increased to 74% between 1997 and 2012. However, temporal access to orphan drugs is slower in Canada: in a head-on comparison of 40 matched drugs, only two were submitted and four were approved first in Canada; moreover, the mean review time in Canada (423 days) was longer than that in the US (mean = 341 days), a statistically significant difference (t[39] = 2.04, p = 0.048). These results raise questions about what motivated Canada's apparent shift in orphan drug policy. Twit Text FOAVip Quelques chiffres derrière la décision du Canada d'adopter une politique sur les médicaments orphelins: approbations pour les médicaments orphelins des États-Unis, 1997-2012 ????Healthc Policy http://www.kidney.de/pget.php?&tw=1&pmid=27232238 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27232238 #FOAvip English Wikipedia <ref>{{Cite pmid|27232238 }}</ref> Quelques chiffres derrière la décision du Canada d'adopter une politique sur les médicaments orphelins: approbations pour les médicaments orphelins des États-Unis, 1997-2012 #MMPMID27232238 Herder M ; Krahn TM Healthc Policy 2016[May]; 11 (4 ): 70-81 PMID27232238 show ga We examined whether access to US-approved orphan drugs in Canada has changed between 1997 (when Canada chose not to adopt an orphan drug policy) and 2012 (when Canada reversed its policy decision). Specifically, we looked at two dimensions of access to US-approved orphan drugs in Canada: (1) regulatory access; and (2) temporal access. Whereas only 63% of US-approved orphan drugs were granted regulatory approval in 1997, we found that regulatory access to US-approved orphan drugs in Canada increased to 74% between 1997 and 2012. However, temporal access to orphan drugs is slower in Canada: in a head-on comparison of 40 matched drugs, only two were submitted and four were approved first in Canada; moreover, the mean review time in Canada (423 days) was longer than that in the US (mean = 341 days), a statistically significant difference (t[39] = 2.04, p = 0.048). These results raise questions about what motivated Canada's apparent shift in orphan drug policy. |*Orphan Drug Production/legislation & jurisprudence/methods/statistics & numerical data [MESH] |Canada [MESH] |Drug Approval/methods/organization & administration/statistics & numerical data [MESH] |Health Policy [MESH] |Humans [MESH]Quelques chiffres derrière la décision du Canada d'adopter une politiq(epmc).pdf DeepDyve Pubget Overpricing