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10.1186/s12941-016-0147-z http://scihub22266oqcxt.onion/10.1186/s12941-016-0147-z C4869319!4869319 !27188991     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27188991 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Ann+Clin+Microbiol+Antimicrob 2016 ; 15 (1 ): 32 Nephropedia Template TP {{tp|p=27188991 |t=2016. What proportion of Salmonella Typhi cases are detected by blood culture? A systematic literature review |pdf=|usr=}}{{27188991 }} gab.com Text What proportion of Salmonella Typhi cases are detected by blood culture A systematic literature review JO: Ann Clin Microbiol Antimicrob http://www.kidney.de/pget.php?&tw=1&pmid=27188991 #FOAvip Blood culture is often used in definitive diagnosis of typhoid fever while, bone marrow culture has a greater sensitivity and considered reference standard. The sensitivity of blood culture measured against bone marrow culture results in measurement bias because both tests are not fully sensitive. Here we propose a combination of the two cultures as a reference to define true positive S. Typhi cases. Based on a systematic literature review, we identified ten papers that had performed blood and bone marrow culture for S. Typhi in same subjects. We estimated the weighted mean of proportion of cases detected by culture measured against true S. Typhi positive cases using a random effects model. Of 529 true positive S. Typhi cases, 61 % (95 % CI 52-70 %) and 96 % (95 % CI 93-99 %) were detected by blood and bone marrow cultures respectively. Blood culture sensitivity was 66 % (95 % CI 56-75 %) when compared with bone marrow culture results. The use of blood culture sensitivity as a proxy measure to estimate the proportion of typhoid fever cases detected by blood culture is likely to be an underestimate. As blood culture sensitivity is used as a correction factor in estimating typhoid disease burden, epidemiologists and policy makers should account for the underestimation. Twit Text FOAVip What proportion of Salmonella Typhi cases are detected by blood culture A systematic literature review ????Ann Clin Microbiol Antimicrob http://www.kidney.de/pget.php?&tw=1&pmid=27188991 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27188991 #FOAvip English Wikipedia <ref>{{Cite pmid|27188991 }}</ref> What proportion of Salmonella Typhi cases are detected by blood culture? A systematic literature review #MMPMID27188991 Mogasale V ; Ramani E ; Mogasale VV ; Park J Ann Clin Microbiol Antimicrob 2016[May]; 15 (1 ): 32 PMID27188991 show ga Blood culture is often used in definitive diagnosis of typhoid fever while, bone marrow culture has a greater sensitivity and considered reference standard. The sensitivity of blood culture measured against bone marrow culture results in measurement bias because both tests are not fully sensitive. Here we propose a combination of the two cultures as a reference to define true positive S. Typhi cases. Based on a systematic literature review, we identified ten papers that had performed blood and bone marrow culture for S. Typhi in same subjects. We estimated the weighted mean of proportion of cases detected by culture measured against true S. Typhi positive cases using a random effects model. Of 529 true positive S. Typhi cases, 61 % (95 % CI 52-70 %) and 96 % (95 % CI 93-99 %) were detected by blood and bone marrow cultures respectively. Blood culture sensitivity was 66 % (95 % CI 56-75 %) when compared with bone marrow culture results. The use of blood culture sensitivity as a proxy measure to estimate the proportion of typhoid fever cases detected by blood culture is likely to be an underestimate. As blood culture sensitivity is used as a correction factor in estimating typhoid disease burden, epidemiologists and policy makers should account for the underestimation. |Blood Culture/*statistics & numerical data [MESH] |Bone Marrow/*microbiology [MESH] |False Negative Reactions [MESH] |False Positive Reactions [MESH] |Humans [MESH] |Salmonella typhi/growth & development/*isolation & purification [MESH] |Sensitivity and Specificity [MESH]What proportion of Salmonella Typhi cases are detected by blood cultur(epmc).pdf DeepDyve Pubget Overpricing