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10.1073/pnas.1515296113 http://scihub22266oqcxt.onion/10.1073/pnas.1515296113 C4868436!4868436!27114521     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2016 ; 113 (19): 5239-44 Nephropedia Template TP {{tp|p=27114521|t=2016. Blue light reduces organ injury from ischemia and reperfusion |pdf=|usr=}}{{27114521}} gab.com Text Blue light reduces organ injury from ischemia and reperfusion JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27114521 #FOAvip It is well established that light regulates mammalian biology. And yet, we have been unable to define and thus harness the underlying mechanisms so as to apply them to alter the course of human disease. In this study we determine that the spectrum of light is a critical determinant of its effect on critical illness. We show that an acute and short (24 h) exposure to high-illuminance (1,400 lx) blue spectrum (peak 442 nm) light prior to ischemia/reperfusion (I/R) significantly attenuates the degree of organ injury. Our characterization of the biological mechanisms through which blue light beneficially alters the cellular response to I/R provides an opportunity to develop novel therapeutics for the prevention and treatment of many diseases. Twit Text FOAVip Blue light reduces organ injury from ischemia and reperfusion ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=27114521 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27114521 #FOAvip English Wikipedia <ref>{{Cite pmid|27114521}}</ref> Blue light reduces organ injury from ischemia and reperfusion #MMPMID27114521 Yuan D; Collage RD; Huang H; Zhang X; Kautza BC; Lewis AJ; Zuckerbraun BS; Tsung A; Angus DC; Rosengart MR Proc Natl Acad Sci U S A 2016[May]; 113 (19): 5239-44 PMID27114521show ga It is well established that light regulates mammalian biology. And yet, we have been unable to define and thus harness the underlying mechanisms so as to apply them to alter the course of human disease. In this study we determine that the spectrum of light is a critical determinant of its effect on critical illness. We show that an acute and short (24 h) exposure to high-illuminance (1,400 lx) blue spectrum (peak 442 nm) light prior to ischemia/reperfusion (I/R) significantly attenuates the degree of organ injury. Our characterization of the biological mechanisms through which blue light beneficially alters the cellular response to I/R provides an opportunity to develop novel therapeutics for the prevention and treatment of many diseases. äBlue light reduces organ injury from ischemia and reperfusion (epmc).pdf DeepDyve Pubget Overpricing