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Synthesis, toxicity, biocompatibility, and biomedical applications of graphene
and graphene-related materials
#MMPMID27226713
Gurunathan S
; Kim JH
Int J Nanomedicine
2016[]; 11
(?): 1927-45
PMID27226713
show ga
Graphene is a two-dimensional atomic crystal, and since its development it has
been applied in many novel ways in both research and industry. Graphene possesses
unique properties, and it has been used in many applications including sensors,
batteries, fuel cells, supercapacitors, transistors, components of high-strength
machinery, and display screens in mobile devices. In the past decade, the
biomedical applications of graphene have attracted much interest. Graphene has
been reported to have antibacterial, antiplatelet, and anticancer activities.
Several salient features of graphene make it a potential candidate for biological
and biomedical applications. The synthesis, toxicity, biocompatibility, and
biomedical applications of graphene are fundamental issues that require thorough
investigation in any kind of applications related to human welfare. Therefore,
this review addresses the various methods available for the synthesis of
graphene, with special reference to biological synthesis, and highlights the
biological applications of graphene with a focus on cancer therapy, drug
delivery, bio-imaging, and tissue engineering, together with a brief discussion
of the challenges and future perspectives of graphene. We hope to provide a
comprehensive review of the latest progress in research on graphene, from
synthesis to applications.
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