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10.1016/j.mito.2016.04.002 http://scihub22266oqcxt.onion/10.1016/j.mito.2016.04.002 C4860904!4860904 !27085476     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27085476 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mitochondrion 2016 ; 28 (ä): 88-95 Nephropedia Template TP {{tp|p=27085476 |t=2016. Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain |pdf=|usr=}}{{27085476 }} gab.com Text Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain JO: Mitochondrion http://www.kidney.de/pget.php?&tw=1&pmid=27085476 #FOAvip Modifications of cardiolipin (CL) levels or compositions are associated with changes in mitochondrial function in a wide range of pathologies. We have made the discovery that acetaminophen remodels CL fatty acids composition from tetralinoleoyl to linoleoyltrioleoyl-CL, a remodeling that is associated with decreased mitochondrial respiration. Our data show that CL remodeling causes a shift in electron entry from complex II to the ?-oxidation electron transfer flavoprotein quinone oxidoreductase (ETF/QOR) pathway. These data demonstrate that electron entry in the respiratory chain is regulated by CL fatty acid composition and provide proof-of-concept that pharmacological intervention can be used to modify CL composition. Twit Text FOAVip Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain ????Mitochondrion http://www.kidney.de/pget.php?&tw=1&pmid=27085476 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27085476 #FOAvip English Wikipedia <ref>{{Cite pmid|27085476 }}</ref> Cardiolipin fatty acid remodeling regulates mitochondrial function by modifying the electron entry point in the respiratory chain #MMPMID27085476 Vergeade A ; Bertram CC ; Bikineyeva AT ; Zackert WE ; Zinkel SS ; May JM ; Dikalov SI ; Roberts LJ 2nd ; Boutaud O Mitochondrion 2016[May]; 28 (ä): 88-95 PMID27085476 show ga Modifications of cardiolipin (CL) levels or compositions are associated with changes in mitochondrial function in a wide range of pathologies. We have made the discovery that acetaminophen remodels CL fatty acids composition from tetralinoleoyl to linoleoyltrioleoyl-CL, a remodeling that is associated with decreased mitochondrial respiration. Our data show that CL remodeling causes a shift in electron entry from complex II to the ?-oxidation electron transfer flavoprotein quinone oxidoreductase (ETF/QOR) pathway. These data demonstrate that electron entry in the respiratory chain is regulated by CL fatty acid composition and provide proof-of-concept that pharmacological intervention can be used to modify CL composition. |*Electron Transport [MESH] |Acetaminophen/*metabolism [MESH] |Antipyretics/*metabolism [MESH] |Cardiolipins/*metabolism [MESH] |Cell Respiration/drug effects [MESH] |Cells, Cultured [MESH] |Fatty Acids/*metabolism [MESH] |Humans [MESH] |Mitochondria/chemistry/*drug effects [MESH] |Myeloid Progenitor Cells/drug effects/metabolism [MESH]Cardiolipin fatty acid remodeling regulates mitochondrial function by (epmc).pdf DeepDyve Pubget Overpricing