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10.1111/1440-1681.12573 http://scihub22266oqcxt.onion/10.1111/1440-1681.12573 C4860143!4860143!27009880     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Clin+Exp+Pharmacol+Physiol 2016 ; 43 (6): 612-5 Nephropedia Template TP {{tp|p=27009880|t=2016. The initial fall in arterial pressure evoked by endotoxin is mediated by the ventrolateral periaqueductal gray |pdf=|usr=}}{{27009880}} gab.com Text The initial fall in arterial pressure evoked by endotoxin is mediated by the ventrolateral periaqueductal gray JO: Clin Exp Pharmacol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=27009880 #FOAvip This study tested the hypothesis that the initial fall in arterial pressure evoked by lipopolysaccharide (LPS) is mediated by the ventrolateral column of the midbrain periaqueductal gray region (vlPAG). To test this hypothesis, the local anesthetic lidocaine (2%; 0.1 ?l, 0.2 ?l or 1.0 ?l), the delta opioid receptor antagonist naltrindole (2 nmol) or saline was microinjected into the vlPAG of isoflurane-anesthetized rats bilaterally and LPS (1 mg/kg) or saline was administered i.v. 2 min later. Both lidocaine and naltrindole inhibited LPS-evoked hypotension significantly but did not affect arterial pressure in saline-treated control animals. Neither lidocaine nor naltrindole altered heart rate significantly in either LPS-treated or control animals. Microinjection of lidocaine or naltrindole into the dorsolateral PAG was ineffective. These data indicate that the vlPAG plays an important role in the initiation of endotoxic hypotension and further show that delta opioid receptors in the vlPAG participate in the response. Twit Text FOAVip The initial fall in arterial pressure evoked by endotoxin is mediated by the ventrolateral periaqueductal gray ????Clin Exp Pharmacol Physiol http://www.kidney.de/pget.php?&tw=1&pmid=27009880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27009880 #FOAvip English Wikipedia <ref>{{Cite pmid|27009880}}</ref> The initial fall in arterial pressure evoked by endotoxin is mediated by the ventrolateral periaqueductal gray #MMPMID27009880 Millington WR; Yilmaz MS; Feleder C Clin Exp Pharmacol Physiol 2016[Jun]; 43 (6): 612-5 PMID27009880show ga This study tested the hypothesis that the initial fall in arterial pressure evoked by lipopolysaccharide (LPS) is mediated by the ventrolateral column of the midbrain periaqueductal gray region (vlPAG). To test this hypothesis, the local anesthetic lidocaine (2%; 0.1 ?l, 0.2 ?l or 1.0 ?l), the delta opioid receptor antagonist naltrindole (2 nmol) or saline was microinjected into the vlPAG of isoflurane-anesthetized rats bilaterally and LPS (1 mg/kg) or saline was administered i.v. 2 min later. Both lidocaine and naltrindole inhibited LPS-evoked hypotension significantly but did not affect arterial pressure in saline-treated control animals. Neither lidocaine nor naltrindole altered heart rate significantly in either LPS-treated or control animals. Microinjection of lidocaine or naltrindole into the dorsolateral PAG was ineffective. These data indicate that the vlPAG plays an important role in the initiation of endotoxic hypotension and further show that delta opioid receptors in the vlPAG participate in the response. äThe initial fall in arterial pressure evoked by endotoxin is mediated (epmc).pdf DeepDyve Pubget Overpricing