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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Biomark+Cancer 2016 ; 8 (Suppl 2): 15-33 Nephropedia Template TP
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The Present and Future of Biomarkers in Prostate Cancer: Proteomics, Genomics, and Immunology Advancements #MMPMID27168728
Gaudreau PO; Stagg J; Soulières D; Saad F
Biomark Cancer 2016[]; 8 (Suppl 2): 15-33 PMID27168728show ga
Prostate cancer (PC) is the second most common form of cancer in men worldwide. Biomarkers have emerged as essential tools for treatment and assessment since the variability of disease behavior, the cost and diversity of treatments, and the related impairment of quality of life have given rise to a need for a personalized approach. High-throughput technology platforms in proteomics and genomics have accelerated the development of biomarkers. Furthermore, recent successes of several new agents in PC, including immunotherapy, have stimulated the search for predictors of response and resistance and have improved the understanding of the biological mechanisms at work. This review provides an overview of currently established biomarkers in PC, as well as a selection of the most promising biomarkers within these particular fields of development.