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10.1002/dvdy.24222 http://scihub22266oqcxt.onion/10.1002/dvdy.24222 C4858172!4858172!25370311     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dev+Dyn 2015 ; 244 (3): 497-506 Nephropedia Template TP {{tp|p=25370311|t=2015. Vascular patterning sets the stage for macro and micro hepatic architecture |pdf=|usr=}}{{25370311}} gab.com Text Vascular patterning sets the stage for macro and micro hepatic architecture JO: Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=25370311 #FOAvip The liver is a complex organ with a variety of tissue components that require a precise architecture for optimal function of metabolic and detoxification processes. As a result of the delicate orchestration required between the various hepatic tissues, it is not surprising that impairment of hepatic function can be caused by a variety of factors leading to chronic liver disease. Despite the growing rate of chronic liver disease, there are currently few effective treatment options besides orthotopic liver transplantation. Better therapeutic options reside in the potential for genetic and cellular therapies that promote progenitor cell activation aiding de novo epithelial and vascular regeneration, cell replacement, or population of bioartificial hepatic devices. In order to explore this area of new therapeutic potential, it is crucial to understand the factors that promote hepatic function through regulating cell identities and tissue architecture. In this commentary, we review the signals regulating liver cell fates during development and regeneration; and highlight the importance of patterning the hepatic vascular systems to set the groundwork for the macro and micro hepatic architecture of the epithelium. Twit Text FOAVip Vascular patterning sets the stage for macro and micro hepatic architecture ????Dev Dyn http://www.kidney.de/pget.php?&tw=1&pmid=25370311 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25370311 #FOAvip English Wikipedia <ref>{{Cite pmid|25370311}}</ref> Vascular patterning sets the stage for macro and micro hepatic architecture #MMPMID25370311 Cast AE; Walter TJ; Huppert SS Dev Dyn 2015[Mar]; 244 (3): 497-506 PMID25370311show ga The liver is a complex organ with a variety of tissue components that require a precise architecture for optimal function of metabolic and detoxification processes. As a result of the delicate orchestration required between the various hepatic tissues, it is not surprising that impairment of hepatic function can be caused by a variety of factors leading to chronic liver disease. Despite the growing rate of chronic liver disease, there are currently few effective treatment options besides orthotopic liver transplantation. Better therapeutic options reside in the potential for genetic and cellular therapies that promote progenitor cell activation aiding de novo epithelial and vascular regeneration, cell replacement, or population of bioartificial hepatic devices. In order to explore this area of new therapeutic potential, it is crucial to understand the factors that promote hepatic function through regulating cell identities and tissue architecture. In this commentary, we review the signals regulating liver cell fates during development and regeneration; and highlight the importance of patterning the hepatic vascular systems to set the groundwork for the macro and micro hepatic architecture of the epithelium. äVascular patterning sets the stage for macro and micro hepatic archite(epmc).pdf DeepDyve Pubget Overpricing