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pmid25320787      Med+Image+Comput+Comput+Assist+Interv 2014 ; 17 (Pt 3): 97-104
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  • Low-Rank to the Rescue ? Atlas-based Analyses in the Presence of Pathologies #MMPMID25320787
  • Liu X; Niethammer M; Kwitt R; McCormick M; Aylward S
  • Med Image Comput Comput Assist Interv 2014[]; 17 (Pt 3): 97-104 PMID25320787show ga
  • Low-rank image decomposition has the potential to address a broad range of challenges that routinely occur in clinical practice. Its novelty and utility in the context of atlas-based analysis stems from its ability to handle images containing large pathologies and large deformations. Potential applications include atlas-based tissue segmentation and unbiased atlas building from data containing pathologies. In this paper we present atlas-based tissue segmentation of MRI from patients with large pathologies. Specifically, a healthy brain atlas is registered with the low-rank components from the input MRIs, the low-rank components are then re-computed based on those registrations, and the process is then iteratively repeated. Preliminary evaluations are conducted using the brain tumor segmentation challenge data (BRATS ?12).
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