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10.1016/j.cellsig.2011.09.001 http://scihub22266oqcxt.onion/10.1016/j.cellsig.2011.09.001 C4856045!4856045!21914472     free     free     free       Cell+Signal 2011 ; 23 (12): 1921-6 Nephropedia Template TP {{tp|p=21914472|t=2011. Guanylyl cyclase structure, function and regulation |pdf=|usr=}}{{21914472}} gab.com Text Guanylyl cyclase structure, function and regulation JO: Cell Signal http://www.kidney.de/pget.php?&tw=1&pmid=21914472 #FOAvip Nitric oxide, bicarbonate, natriuretic peptides (ANP, BNP and CNP), guanylins, uroguanylins and guanylyl cyclase activating proteins (GCAPs) activate a family of enzymes variously called guanyl, guanylyl or guanylate cyclases that catalyze the conversion of guanosine triphosphate to cyclic guanosine monophosphate (cGMP) and pyrophosphate. Intracellular cyclic GMP is a second messenger that modulates: platelet aggregation, neurotransmission, sexual arousal, gut peristalsis, blood pressure, long bone growth, intestinal fluid secretion, lipolysis, phototransduction, cardiac hypertrophy and oocyte maturation. This review briefly discusses the discovery of cGMP and guanylyl cyclases, then nitric oxide, nitric oxide synthase and soluble guanylyl cyclase are described in slightly greater detail. Finally, the structure, function, and regulation of the individual mammalian single membrane-spanning guanylyl cyclases GC-A, GC-B, GC-C, GC-D, GC-E, GC-F and GC-G are described in greatest detail as determined by biochemical, cell biological and gene-deletion studies. Twit Text FOAVip Guanylyl cyclase structure, function and regulation ????Cell Signal http://www.kidney.de/pget.php?&tw=1&pmid=21914472 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=21914472 #FOAvip English Wikipedia <ref>{{Cite pmid|21914472}}</ref> Guanylyl cyclase structure, function and regulation #MMPMID21914472 Potter LR Cell Signal 2011[Dec]; 23 (12): 1921-6 PMID21914472show ga Nitric oxide, bicarbonate, natriuretic peptides (ANP, BNP and CNP), guanylins, uroguanylins and guanylyl cyclase activating proteins (GCAPs) activate a family of enzymes variously called guanyl, guanylyl or guanylate cyclases that catalyze the conversion of guanosine triphosphate to cyclic guanosine monophosphate (cGMP) and pyrophosphate. Intracellular cyclic GMP is a second messenger that modulates: platelet aggregation, neurotransmission, sexual arousal, gut peristalsis, blood pressure, long bone growth, intestinal fluid secretion, lipolysis, phototransduction, cardiac hypertrophy and oocyte maturation. This review briefly discusses the discovery of cGMP and guanylyl cyclases, then nitric oxide, nitric oxide synthase and soluble guanylyl cyclase are described in slightly greater detail. Finally, the structure, function, and regulation of the individual mammalian single membrane-spanning guanylyl cyclases GC-A, GC-B, GC-C, GC-D, GC-E, GC-F and GC-G are described in greatest detail as determined by biochemical, cell biological and gene-deletion studies. äGuanylyl cyclase structure, function and regulation (epmc).pdf DeepDyve Pubget Overpricing