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Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 BMC+Gastroenterol 2016 ; 16 (ä): ä Nephropedia Template TP
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An appraisal of clinical practice guidelines for constipation: a right attitude towards to guidelines #MMPMID27142422
Tian H; Ding C; Gong J; Ge X; McFarland LV; Gu L; Chen Q; Ma C; Zhu W; Li J; Li N
BMC Gastroenterol 2016[]; 16 (ä): ä PMID27142422show ga
Background: Clinical practice guidelines (CPGs) are formally developed statements that assist users to provide proper health care for a kind of disease and play a significant contribution in healthcare system. This study report the methodological quality of CPGs on constipation. Methods: The ?Appraisal of Guidelines and Research and Evaluation? (AGREEII) instrument was developed to determine the quality of CPGs. A comprehensive search was developed using five databases and three guideline websites until/up to December, 2015. Four independent authors evaluated the methodological issues of the CPGs by the AGREEII instrument. Results: We identified 22 relevant guidelines on constipation from 1234 citations. The overall agreement among evaluators was 0.84 using the intra-class correlation coefficient. The mean AGREEII scores for the domains ?scope and purpose? (51.77) and ?rigor of development? (56.73) were moderate; afterward, three domains ?stakeholder involvement? (32.23), ?editorial independence? (29.59) and ?applicability? (29.14) were low scores. The ?clarity and presentation? (23.73) had the lowest scores. Conclusion: Although existing constipation guidelines may accurately reflect current clinical practices, many guidelines? methodological quality is low. Therefore, more emphasis and attentions should be taken to the development of high-quality guidelines.