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10.1038/jes.2015.69

http://scihub22266oqcxt.onion/10.1038/jes.2015.69
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suck abstract from ncbi


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pmid26531802      J+Expo+Sci+Environ+Epidemiol 2016 ; 26 (5): 452-7
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  • Contribution of breast milk and formula to arsenic exposure during the first year of life in a U S prospective cohort #MMPMID26531802
  • Carignan CC; Karagas MR; Punshon T; Gilbert-Diamond D; Cottingham KL
  • J Expo Sci Environ Epidemiol 2016[Sep]; 26 (5): 452-7 PMID26531802show ga
  • Arsenic is a carcinogen that can also affect the cardiac, respiratory, neurological and immune systems. Children have higher dietary arsenic exposure than adults due to their more restricted diets and greater intake per unit body mass. We evaluated the potential contributions of breast milk and formula to arsenic exposure throughout the first year of life for 356 infants in the prospective New Hampshire Birth Cohort Study (NHBCS) using infant diets reported by telephone at 4, 8 and 12 months of age; measured household water arsenic concentrations; and literature data. Based on our central-tendency models, population-wide geometric mean (GM) estimated arsenic exposures in the NHBCS were relatively low, decreasing from 0.1 ?g kg?1 d?1 at 4 months of age to 0.07 ?g kg?1 d?1 at 12 months of age. At all three time points, exclusively formula-fed infants had GM arsenic exposures ~8 times higher than exclusively breastfed infants due to arsenic in both tap water and formula powder. Estimated maximum exposures reached 9 ?g kg?1 d?1 among exclusively formula-fed infants in households with high tap water arsenic (80 ?g/L). Overall, modeled arsenic exposures via breast milk and formula were low throughout the first year of life, unless formula was prepared with arsenic-contaminated tap water.
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