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10.1084/jem.20151948

http://scihub22266oqcxt.onion/10.1084/jem.20151948
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C4854736!4854736!27091843
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suck abstract from ncbi


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pmid27091843      J+Exp+Med 2016 ; 213 (5): 667-75
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  • TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques #MMPMID27091843
  • Wang Y; Ulland TK; Ulrich JD; Song W; Tzaferis JA; Hole JT; Yuan P; Mahan TE; Shi Y; Gilfillan S; Cella M; Grutzendler J; DeMattos RB; Cirrito JR; Holtzman DM; Colonna M
  • J Exp Med 2016[May]; 213 (5): 667-75 PMID27091843show ga
  • Wang et al. report that TREM2 protects mice from Alzheimer's disease by enabling resident microglia to insulate and alter A? plaque structure, thereby limiting neuritic damage.
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