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Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Radiother+Oncol 2015 ; 117 (2): 382-5 Nephropedia Template TP
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Specificity of Vascular Endothelial Growth Factor Treatment for Radiation Necrosis #MMPMID26376163
Radiother Oncol 2015[Nov]; 117 (2): 382-5 PMID26376163show ga
Recently, radiation induced necrosis in the brain has been treated using bevacizumab, an anti-VEGF antibody. We validated the VEGF specificity by comparing the therapeutic efficacy of anti-VEGF with non-specific isotype control antibody. Additionally, we found that VEGF over-expression and RN developed simultaneously, which precludes preventative anti-VEGF treatment.