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10.1016/j.survophthal.2005.12.001 http://scihub22266oqcxt.onion/10.1016/j.survophthal.2005.12.001 C4853913!4853913!16500214     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Surv+Ophthalmol 2006 ; 51 (2): 137-52 Nephropedia Template TP {{tp|p=16500214|t=2006. The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration |pdf=|usr=}}{{16500214}} gab.com Text The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration JO: Surv Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=16500214 #FOAvip Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is a complex disease to study because of the potential role of demographic, environmental, and other systemic risk factors, such as age, sex, race, light exposure, diet, smoking, and underlying cardiovascular disease which may contribute to the pathogenesis of this disease. Recently, single nucleotide polymorphisms, DNA sequence variations found within the complement Factor H gene, have been found to be strongly associated with the development of AMD in Caucasians. One single nucleotide polymorphism, Tyr402His, was associated with approximately 50% of AMD cases. We review recent developments in the molecular biology of AMD, including single nucleotide polymorphisms within the Factor H gene, which may predispose individuals to the susceptibility of AMD as well as single nucleotide polymorphisms that may confer a protective effect. Taken together these findings help to provide new insights into the central issues surrounding the pathogenesis of AMD. Twit Text FOAVip The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration ????Surv Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=16500214 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=16500214 #FOAvip English Wikipedia <ref>{{Cite pmid|16500214}}</ref> The Role of Inflammation in the Pathogenesis of Age-related Macular Degeneration #MMPMID16500214 Donoso LA; Kim D; Frost A; Callahan A; Hageman G Surv Ophthalmol 2006[Mar]; 51 (2): 137-52 PMID16500214show ga Age-related macular degeneration (AMD), the leading cause of blindness in the elderly, is a complex disease to study because of the potential role of demographic, environmental, and other systemic risk factors, such as age, sex, race, light exposure, diet, smoking, and underlying cardiovascular disease which may contribute to the pathogenesis of this disease. Recently, single nucleotide polymorphisms, DNA sequence variations found within the complement Factor H gene, have been found to be strongly associated with the development of AMD in Caucasians. One single nucleotide polymorphism, Tyr402His, was associated with approximately 50% of AMD cases. We review recent developments in the molecular biology of AMD, including single nucleotide polymorphisms within the Factor H gene, which may predispose individuals to the susceptibility of AMD as well as single nucleotide polymorphisms that may confer a protective effect. Taken together these findings help to provide new insights into the central issues surrounding the pathogenesis of AMD. äThe Role of Inflammation in the Pathogenesis of Age-related Macular De(epmc).pdf DeepDyve Pubget Overpricing