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10.1038/ncomms11106 http://scihub22266oqcxt.onion/10.1038/ncomms11106 C4853467!4853467!27112789     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2016 ; 7 (ä): ä Nephropedia Template TP {{tp|p=27112789|t=2016. Diverse human extracellular RNAs are widely detected in human plasma |pdf=|usr=}}{{27112789}} gab.com Text Diverse human extracellular RNAs are widely detected in human plasma JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=27112789 #FOAvip There is growing appreciation for the importance of non-protein-coding genes in development and disease. Although much is known about microRNAs, limitations in bioinformatic analyses of RNA sequencing have precluded broad assessment of other forms of small-RNAs in humans. By analysing sequencing data from plasma-derived RNA from 40 individuals, here we identified over a thousand human extracellular RNAs including microRNAs, piwi-interacting RNA (piRNA), and small nucleolar RNAs. Using a targeted quantitative PCR with reverse transcription approach in an additional 2,763 individuals, we characterized almost 500 of the most abundant extracellular transcripts including microRNAs, piRNAs and small nucleolar RNAs. The presence in plasma of many non-microRNA small-RNAs was confirmed in an independent cohort. We present comprehensive data to demonstrate the broad and consistent detection of diverse classes of circulating non-cellular small-RNAs from a large population. Twit Text FOAVip Diverse human extracellular RNAs are widely detected in human plasma ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=27112789 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27112789 #FOAvip English Wikipedia <ref>{{Cite pmid|27112789}}</ref> Diverse human extracellular RNAs are widely detected in human plasma #MMPMID27112789 Freedman JE; Gerstein M; Mick E; Rozowsky J; Levy D; Kitchen R; Das S; Shah R; Danielson K; Beaulieu L; Navarro FCP; Wang Y; Galeev TR; Holman A; Kwong RY; Murthy V; Tanriverdi SE; Koupenova M; Mikhalev E; Tanriverdi K Nat Commun 2016[]; 7 (ä): ä PMID27112789show ga There is growing appreciation for the importance of non-protein-coding genes in development and disease. Although much is known about microRNAs, limitations in bioinformatic analyses of RNA sequencing have precluded broad assessment of other forms of small-RNAs in humans. By analysing sequencing data from plasma-derived RNA from 40 individuals, here we identified over a thousand human extracellular RNAs including microRNAs, piwi-interacting RNA (piRNA), and small nucleolar RNAs. Using a targeted quantitative PCR with reverse transcription approach in an additional 2,763 individuals, we characterized almost 500 of the most abundant extracellular transcripts including microRNAs, piRNAs and small nucleolar RNAs. The presence in plasma of many non-microRNA small-RNAs was confirmed in an independent cohort. We present comprehensive data to demonstrate the broad and consistent detection of diverse classes of circulating non-cellular small-RNAs from a large population. äDiverse human extracellular RNAs are widely detected in human plasma (epmc).pdf DeepDyve Pubget Overpricing